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AB144600

NPC-15437, PKC inhibitor

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(1 Publication)

MW 511.6 Da, Purity >98%. PKC inhibitor (IC50 = 19 μM). Interacts with regulatory domain at residues 12-42. Neuroprotective agent. Active in vivo and in vitro.
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Chemical Structure - NPC-15437, PKC inhibitor (AB144600)
  • Chemical Structure

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Chemical Structure - NPC-15437, PKC inhibitor (AB144600)

2D chemical structure image of ab144600, NPC-15437, PKC inhibitor

Key facts

CAS number

136449-85-9

Purity

>98%

Molecular weight

511.6 Da

Molecular formula

C<sub>2</sub><sub>5</sub>H<sub>5</sub><sub>2</sub>Cl<sub>2</sub>N<sub>4</sub>O<sub>2</sub>

PubChem

19778249

Nature

Synthetic

Solubility

Soluble in water to 25 mM

Biochemical name

2,6-diamino-N-[(1-tridecanoylpiperidin-2-yl)methyl]hexanamide;dihydrochloride

Biological description

PKC inhibitor (IC50 = 19 μM). Interacts with regulatory domain at residues 12-42. Neuroprotective agent. Active in vivo and in vitro.

Canonical smiles

CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)C(CCCCN)N.Cl.Cl

InChi

InChI=1S/C25H50N4O2.2ClH/c1-2-3-4-5-6-7-8-9-10-11-18-24(30)29-20-15-13-16-22(29)21-28-25(31)23(27)17-12-14-19-26;;/h22-23H,2-21,26-27H2,1H3,(H,28,31);2*1H

InChiKey

RISSBZWRJRRXTD-UHFFFAOYSA-N

IUPAC Name

2,6-diamino-N-[(1-tridecanoylpiperidin-2-yl)methyl]hexanamide;dihydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 13:1178021 PubMed37483514

2023

Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Veronika Liskova,Barbora Chovancova,Petr Babula,Ingeborg Rezuchova,Kristina Ploth Pavlov,Miroslava Matuskova,Olga Krizanova
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