Oleanolic acid, Natural triterpenoid
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MW 456.7 Da, Purity >96%. Natural triterpenoid. Various pharmacological attributes. Antiviral, anti-inflammatory, antiangiogenic, antiapoptotic and antitumor activities in vitro and in vivo.
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70Z-SHP, ACP1, AI604853, AI838772, AW493413, Acid phosphatase 1 soluble, Acid phosphatase of erythrocyte, Adipocyte acid phosphatase, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, B220, BG 37, BPTP3, CD 45, CD142, CD142 antigen, CD45 antigen, CD45R, CDC25HU2, Cdc 25B, Cdc25m2, Cell division cycle 25 homolog B, Cell division cycle 25B, Cell division cycle 25B isoform 1, Cell division cycle 25B isoform 2, Cell division cycle 25B isoform 3, Cell division cycle 25B isoform 4, Cell division cycle 25B isoform 5, Coagulation factor III, Coagulation factor III (thromboplastin tissue factor), Cytoplasmic phosphotyrosyl protein phosphatase, DNA directed DNA polymerase beta, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DPOLB_HUMAN, DUS3_HUMAN, Dual specificity phosphatase 3, Dual specificity phosphatase Cdc25B, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, EC 3.1.3.48, F3, FLJ11090, FLJ17960, FLJ43335, FLJ45062, FLJ45567, G protein coupled bile acid receptor BG 37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GP180, GPBAR 1, GPBAR_HUMAN, GPCR, GPCR 19, GPR 131, Group IB phospholipase A2, Group IB secretory phospholipase A2, HAAP, HCP, HCPH, HPTP1C, Hematopoietic cell phosphatase, Hematopoietic cell protein-tyrosine phosphatase, JMML, L-CA, LAR protein, LARFN5C, LARS, LCA homolog, LMW-PTP, LMW-PTPase, Leukocyte antigen related, Leukocyte antigen related (LAR) PTP receptor, Leukocyte antigen related PTP receptor, Leukocyte antigen related tyrosine phosphatase, Leukocyte common antigen, Leukocyte common antigen related, Low molecular weight cytosolic acid phosphatase, Low molecular weight phosphotyrosine protein phosphatase, Ly-5, M-BAR, M-phase inducer phosphatase 2, METCDS, MGC104252, MGC112732, MGC119834, MGC119835, MGC125976, MGC131774, MGC14433, MGC40597, MPIP2_HUMAN, Membrane bile acid receptor, Membrane-type receptor for bile acids, NF kappa B p65delta3, NFKB3, NFkB p65, Non receptor tyrosine phosphatase 1, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor kappa-B, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, OTTHUMP00000166107, OTTHUMP00000166108, OTTHUMP00000233473, OTTHUMP00000233474, OTTHUMP00000233475, OTTHUMP00000233476, OTTHUMP00000233900, PA21B_HUMAN, PAP1, PAP2, PLA 2, PLA2A, PPAC_HUMAN, PPLA 2, PTN11_HUMAN, PTN1_HUMAN, PTN2_HUMAN, PTN6_HUMAN, PTP-1B, PTP-1C, PTP-1D, PTP-2C, PTPN 1, PTPN 2, PTPN11, PTPRC_HUMAN, PTPRF protein, PTPRF_HUMAN, PTPT, PTPase, Phosphatidylcholine 2-acylhydrolase, Phosphatidylcholine 2-acylhydrolase 1B, Phospholipase A2, Phospholipase A2 group IB, Phospholipase A2 group IB (pancreas), Pol B, Pol beta, Polymerase (DNA directed) beta, Protein Tyrosine Phosphatase Receptor Type F, Protein phosphotyrosylphosphatase 1B, Protein tyrosine phosphatase, Protein tyrosine phosphatase 2, Protein tyrosine phosphatase non receptor type 1, Protein tyrosine phosphatase non receptor type 11, Protein tyrosine phosphatase non receptor type 2, Protein tyrosine phosphatase non receptor type 6, Protein tyrosine phosphatase placental, Protein tyrosine phosphatase receptor type F polypeptide, Protein tyrosine phosphatase, receptor type, C, Protein tyrosine phosphatase, receptor type, c polypeptide, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase SHP-1, Ptpn6, Purple acid phosphatase, RP24-311F12.2, Receptor linked protein tyrosine phosphatase LAR, Receptor type tyrosine protein phosphatase F precursor, Receptor-type tyrosine-protein phosphatase C, Receptor-type tyrosine-protein phosphatase F, Red cell acid phosphatase 1, SAP-2, SCAN1, SH-PTP1, SH-PTP2, SH-PTP3, SH2 domain containing protein tyrosine phosphatase 2, SHP 1L, SHP-2, Serine/threonine specific protein phosphatase, T-cell protein-tyrosine phosphatase, T200, T200 Glycoprotein, T200 leukocyte common antigen, TCELLPTP, TF65_HUMAN, TFA, TF_HUMAN, TGR 5, TYDP, TYDP1_HUMAN, Thromboplastin, Tissue factor, Transcription factor NFKB3, Transcription factor p65, Tyr-DNA phosphodiesterase 1, Tyrosine-protein phosphatase non-receptor type 1, Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 2, Tyrosine-protein phosphatase non-receptor type 6, Tyrosyl-DNA phosphodiesterase 1, V rel avian reticuloendotheliosis viral oncogene homolog A, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65, VHR, Vaccinia H1-related phosphatase, Vaccinia virus phosphatase VH1 related, hBG 37, hGPCR 19, nfkappabp65, p65, p65 NF kappaB, p65 NFkB, phosphatase, acid, of erythrocyte, relA, sPLA2IB, testicular secretory protein Li 37, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)), v rel reticuloendotheliosis viral oncogene homolog A (avian)
- Chemical Structure
Lab
Chemical Structure - Oleanolic acid, Natural triterpenoid (AB141066)
2D chemical structure image of ab141066, Oleanolic acid, Natural triterpenoid
Properties and storage information
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Appropriate long-term storage conditions
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Proteins such as CD45RO play roles in signal transduction within immune cells. This phosphatase does not function alone; it is part of larger complexes that regulate immune responses. Targets like NF-kB p65 form transcription complexes that manage inflammation and cell survival. Furthermore Acid phosphatase/ACP1 facilitates cellular phosphate metabolism supporting various cellular processes. DNA Polymerase beta functions importantly in the base excision repair complex addressing DNA damage efficiently. These targets act synergistically with natural immunomodulators to maintain cellular and systemic homeostasis.
Pathways
Proteins like CD45RO and GPCR TGR5 participate in the immune and metabolic signaling pathways. CD45RO influences pathways involving kinases such as Lck and Fyn which are critical to T-cell receptor mediated signal transduction. In parallel GPCR TGR5 modulates metabolic pathways influencing energy expenditure and bile acid signaling. The nuclear factor NF-kB p65 is a significant player in pathways controlling immune and inflammatory responses interacting with ather at a molecular level. Proper regulation of these pathways ensures balanced cellular physiology and immune responses.
Product promise
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