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AB120938

Olomoucine, ATP-competitive CDK inhibitor

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Olomoucine (CAS No: 101622-51-9)(ab120938). ATP-competitive CDK inhibitor (IC50 values are 7 (CDC2/cyclin B), 7 (CDK2/cyclin A), 7 (CDK2/cyclin E), 3 (CDK/p35 kinase) and 25 µM (ERK1/p44 MAPK)). Inhibits cell cycle progression in vitro and in vivo MW 298.35. Purity >98%.

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Chemical Structure - Olomoucine, ATP-competitive CDK inhibitor (AB120938)
  • Chemical Structure

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Chemical Structure - Olomoucine, ATP-competitive CDK inhibitor (AB120938)

2D chemical structure image of ab120938, Olomoucine, ATP-competitive CDK inhibitor

Key facts

CAS number

101622-51-9

Purity

>98%

Formulation

Constituents: 100% Olomoucine

Molecular weight

298.35 g/mol

Molecular formula

C<sub>1</sub><sub>5</sub>H<sub>1</sub><sub>8</sub>N<sub>6</sub>O

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Soluble in ethanol to 25 mM

Biological description

ATP-competitive CDK inhibitor (IC50 values are 7 (CDC2/cyclin B), 7 (CDK2/cyclin A), 7 (CDK2/cyclin E), 3 (CDK/p35 kinase) and 25 μM (ERK1/p44 MAPK)). Inhibits cell cycle progression in vitro and in vivo.

Canonical smiles

OCCNC1NC(NCC2CCCCC2)C2NCN(C)C2N1

IUPAC Name

6-Benzylamino-2-(2-hydroxyethylamino)-9-methylpurine

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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Product promise

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