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MW 371.9 Da, Purity >98%. Potent, reversible PLA2 inhibitor (IC50 = 7 µM). Cell-permeable. Active in *ex vivo* preparations.

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Images

Chemical Structure - ONO-RS-082, phospholipase A2 (PLA2) inhibitor (AB141760), expandable thumbnail

Publications

Key facts

CAS number

99754-06-0

Purity

> 98%

Form

Solid

Molecular weight

371.9 Da

Molecular formula

C21H22ClNO3

PubChem identifier

6438389

Nature

Synthetic

Recommended products

MW 371.9 Da, Purity >98%. Potent, reversible PLA2 inhibitor (IC50 = 7 µM). Cell-permeable. Active in *ex vivo* preparations.

Key facts

Purity

> 98%

PubChem identifier

6438389

Solubility

Soluble in DMSO to 50 mM (with warming). Soluble in ethanol to 25 mM (with warming).

Biochemical name

2-(4-Amylcinnamoyl)amino-4-chlorobenzoic acid

Biological description

Potent, reversible PLA2 inhibitor (IC50 = 7 µM). Cell-permeable. Active in *ex vivo* preparations.

Canonical SMILES

CCCCCC1=CC=C(C=C1)C=CC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O

Isomeric SMILES

CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=C(C=CC(=C2)Cl)C(=O)O

InChI

InChI=1S/C21H22ClNO3/c1-2-3-4-5-15-6-8-16(9-7-15)10-13-20(24)23-19-14-17(22)11-12-18(19)21(25)26/h6-14H,2-5H2,1H3,(H,23,24)(H,25,26)/b13-10+

InChIKey

MDVFITMPFHDRBZ-JLHYYAGUSA-N

IUPAC name

4-chloro-2-[[(E)-3-(4-pentylphenyl)prop-2-enoyl]amino]benzoic acid

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions

Product promise

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1 product image

  • Chemical Structure - ONO-RS-082, phospholipase A2 (PLA2) inhibitor (ab141760), expandable thumbnail

    Chemical Structure - ONO-RS-082, phospholipase A2 (PLA2) inhibitor (ab141760)

    2D chemical structure image of ab141760, ONO-RS-082, phospholipase A2 (PLA2) inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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