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AB141761

PACOCF3, phospholipase A2 inhibitor

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MW 308.4 Da, Purity >98%. Selective phospholipase A2 inhibitor (IC50 = 3.8 μM). Four times more potent than arachidonyl trifluoromethyl ketone (ab120350). Alters Ca2+ signaling and impairs memory acquisition and retrieval. Active *in vitro*. Centrally active *in vivo*.
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Chemical Structure - PACOCF3, phospholipase A2 inhibitor (AB141761)
  • Chemical Structure

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Chemical Structure - PACOCF3, phospholipase A2 inhibitor (AB141761)

2D chemical structure image of ab141761, PACOCF3, phospholipase A2 inhibitor

Key facts

CAS number

141022-99-3

Purity

>98%

Form

Solid

form

Molecular weight

308.4 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>3</sub><sub>1</sub>F<sub>3</sub>O

PubChem

4670

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Soluble in ethanol to 50 mM

Biochemical name

1,1,1-Trifluoroheptadecan-2-one

Biological description

Selective phospholipase A2 inhibitor (IC50 = 3.8 μM). Four times more potent than arachidonyl trifluoromethyl ketone (ab120350). Alters Ca2+ signaling and impairs memory acquisition and retrieval. Active *in vitro*. Centrally active *in vivo*.

Canonical smiles

CCCCCCCCCCCCCCCC(=O)C(F)(F)F

InChi

InChI=1S/C17H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(21)17(18,19)20/h2-15H2,1H3

InChiKey

MAHYXYTYTLCTQD-UHFFFAOYSA-N

IUPAC Name

1,1,1-trifluoroheptadecan-2-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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