PBFI AM, fluorescent K+ binding probe

Key facts

CAS number

124549-23-1

Purity

>94%

Form

Solid

form

Molecular weight

1171.1 Da

Molecular formula

C₅₈H₆₂N₂O₂₄

PubChem

3283499

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

Pbfi-AM

Biological description

Cell-permeable, fluorescent K+ binding probe (Kd = 5 mM). Active *in vitro*. Non-specific esterases hydrolyze the AM esters to produce the water-soluble form of PBFI.Excitation is 340/390 nm.

Canonical smiles

CC(=O)OCOC(=O)C1=CC(=C(C=C1)C2=CC3=CC(=C(C=C3O2)N4CCOCCOCCN(CCOCCOCC4)C5=C(C=C6C=C(OC6=C5)C7=C(C=C(C=C7)C(=O)OCOC(=O)C)C(=O)OCOC(=O)C)OC)OC)C(=O)OCOC(=O)C

InChi

InChI=1S/C58H62N2O24/c1-35(61)75-31-79-55(65)39-7-9-43(45(23-39)57(67)81-33-77-37(3)63)51-25-41-27-53(69-5)47(29-49(41)83-51)59-11-15-71-19-21-73-17-13-60(14-18-74-22-20-72-16-12-59)48-30-50-42(28-54(48)70-6)26-52(84-50)44-10-8-40(56(66)80-32-76-36(2)62)24-46(44)58(68)82-34-78-38(4)64/h7-10,23-30H,11-22,31-34H2,1-6H3

InChiKey

AUKRBWNSOWVABU-UHFFFAOYSA-N

IUPAC Name

bis(acetyloxymethyl) 4-[6-[16-[2-[2,4-bis(acetyloxymethoxycarbonyl)phenyl]-5-methoxy-1-benzofuran-6-yl]-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]-5-methoxy-1-benzofuran-2-yl]benzene-1,3-dicarboxylate

Excitation/Emission

Ex: 340nm, Em: 500nm