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MW 462.7 Da, Purity >99%. Alkylphospholipid and Akt inhibitor. Antiproliferative activity in vitro (IC50 = 0.6 - 8.9 μM). Anticancer activity in vivo. Orally active.

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Images

Chemical Structure - Perifosine, Akt inhibitor (AB142055), expandable thumbnail

Key facts

CAS number
157716-52-4
Purity
> 99%
Form
Solid
Molecular weight
462.7 Da
Molecular formula
C25H53NO4P+
PubChem identifier
148178
Nature
Synthetic

Target data

Recommended products

MW 462.7 Da, Purity >99%. Alkylphospholipid and Akt inhibitor. Antiproliferative activity in vitro (IC50 = 0.6 - 8.9 μM). Anticancer activity in vivo. Orally active.

Key facts

Purity
> 99%
PubChem identifier
148178
Solubility

Soluble in water to 10 mM.

Soluble in ethanol to 25 mM.

Biochemical name
(1,1-Dimethylpiperidin-1-ium-4-yl) octadecyl hydrogen phosphate
Biological description

Alkylphospholipid and Akt inhibitor. Antiproliferative activity in vitro (IC50 = 0.6 - 8.9 μM). Anticancer activity in vivo. Orally active.

Canonical SMILES
CCCCCCCCCCCCCCCCCCOP(=O)(O)OC1CC[N+](CC1)(C)C
InChI
InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3/p+1
InChIKey
SZFPYBIJACMNJV-UHFFFAOYSA-O
IUPAC name
(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl hydrogen phosphate

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Notes

This product is manufactured by BioVision, an Abcam company and was previously called 1592 Perifosine (KRX-0401). 1592-25 is the same size as the 25 mg size of ab142055.

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1 product image

  • Chemical Structure - Perifosine, Akt inhibitor (ab142055), expandable thumbnail

    Chemical Structure - Perifosine, Akt inhibitor (ab142055)

    2D chemical structure image of ab142055, Perifosine, Akt inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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