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AB273614

PF-04929113 (SNX-5422)

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MW 521.5 Da, Purity >99%. Potent and selective Hsp90 inhibitor (IC50 = 50 nM). A Her-2 degradation inducer (IC50 = 37 nM).
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Chemical Structure - PF-04929113 (SNX-5422) (AB273614)
  • Chemical Structure

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Chemical Structure - PF-04929113 (SNX-5422) (AB273614)

Chemical structure of PF-04929113 (SNX-5422), 908115-27-5

Key facts

CAS number

908115-27-5

Purity

>99%

Form

Solid

form

Molecular weight

521.5 Da

Molecular formula

C<sub>2</sub><sub>5</sub>H<sub>3</sub><sub>0</sub>F<sub>3</sub>N<sub>5</sub>O<sub>4</sub>

PubChem

44195571

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Biochemical name

Snx-5422

Biological description

Potent and selective Hsp90 inhibitor (IC50 = 50 nM). A Her-2 degradation inducer (IC50 = 37 nM).

Canonical smiles

CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C

InChi

InChI=1S/C25H30F3N5O4/c1-24(2)10-18-21(19(34)11-24)22(25(26,27)28)32-33(18)14-5-8-16(23(30)36)17(9-14)31-13-3-6-15(7-4-13)37-20(35)12-29/h5,8-9,13,15,31H,3-4,6-7,10-12,29H2,1-2H3,(H2,30,36)

InChiKey

AVDSOVJPJZVBTC-UHFFFAOYSA-N

IUPAC Name

[4-[2-carbamoyl-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]anilino]cyclohexyl] 2-aminoacetate

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Product details

For obtaining a higher solubility, please warm the tube at 37°C and shake in the ultrasonic bath for a while.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

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Product promise

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