Skip to main content

MW 393.5 Da, Purity >93%. Selective P-glycoprotein inhibitor. Reverses Pgp mediated drug resistance in NCI/ADR cells. Shows synergistic effects with doxorubicin (ab120629) in vivo. .

Be the first to review this product! Submit a review

Images

Chemical Structure - PGP 4008, P-glycoprotein inhibitor (AB145191), expandable thumbnail

Key facts

CAS number
365565-02-2
Purity
> 93%
Molecular weight
393.5 Da
Molecular formula
C26H23N3O
PubChem identifier
9821937
Nature
Synthetic

Target data

Recommended products

MW 393.5 Da, Purity >93%. Selective P-glycoprotein inhibitor. Reverses Pgp mediated drug resistance in NCI/ADR cells. Shows synergistic effects with doxorubicin (ab120629) in vivo. .

Key facts

Purity
> 93%
PubChem identifier
9821937
Solubility

Soluble in ethanol to 5 mM.

Soluble in DMSO to 50 mM.

Biochemical name
Unii-M7jjr8HX5D
Biological description

Selective P-glycoprotein inhibitor. Reverses Pgp mediated drug resistance in NCI/ADR cells. Shows synergistic effects with doxorubicin (ab120629) in vivo.

Canonical SMILES
C1CN(C2=NC3=CC=CC=C3C(=C21)NC(=O)CC4=CC=CC=C4)CC5=CC=CC=C5
InChI
InChI=1S/C26H23N3O/c30-24(17-19-9-3-1-4-10-19)28-25-21-13-7-8-14-23(21)27-26-22(25)15-16-29(26)18-20-11-5-2-6-12-20/h1-14H,15-18H2,(H,27,28,30)
InChIKey
HVIAKQBMYMKWII-UHFFFAOYSA-N
IUPAC name
N-(1-benzyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - PGP 4008, P-glycoprotein inhibitor (ab145191), expandable thumbnail

    Chemical Structure - PGP 4008, P-glycoprotein inhibitor (ab145191)

    2D chemical structure image of ab145191, PGP 4008, P-glycoprotein inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com