PHCCC, allosteric potentiator at mGlu4

Key facts

CAS number

179068-02-1

Purity

>98%

Form

Solid

form

Molecular weight

294.3 Da

Molecular formula

C₁₇H₁₄N₂O₃

PubChem

5866327

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

Phccc

Biological description

Selective allosteric potentiator of mGlu4. Anti-Parkinson and anxiolytic effects *in vivo*. Also antagonist at Group I metabotropic receptors.

Canonical smiles

C1C2C1(OC3=CC=CC=C3C2=NO)C(=O)NC4=CC=CC=C4

Isomeric smiles

C1C\2C1(OC3=CC=CC=C3/C2=N/O)C(=O)NC4=CC=CC=C4

InChi

InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15-

InChiKey

FPXPIEZPAXSELW-CYVLTUHYSA-N

IUPAC Name

(7E)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide