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AB120931

PIK 75 hydrochloride, p110alpha PI3K inhibitor

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MW 488.74 g/mol, Purity >98%. Selective inhibitor of p110α (IC50 values are 5.8, 76 nM and 1.3 μM at p110α, p110γ and p110β, respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and activation of mTORC1. Cell-permeable.
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Chemical Structure - PIK 75 hydrochloride, p110alpha PI3K inhibitor (AB120931)
  • Chemical Structure

Lab

Chemical Structure - PIK 75 hydrochloride, p110alpha PI3K inhibitor (AB120931)

2D chemical structure image of ab120931, PIK 75 hydrochloride, p110alpha PI3K inhibitor

Key facts

CAS number

372196-77-5

Purity

>98%

Molecular weight

488.74 g/mol

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>4</sub>BrN<sub>5</sub>O<sub>4</sub>S.HCl

Nature

Synthetic

Solubility

Soluble in DMSO to 5 mM

Biological description

Selective inhibitor of p110α (IC50 values are 5.8, 76 nM and 1.3 μM at p110α, p110γ and p110β, respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and activation of mTORC1. Cell-permeable.

Isomeric smiles

BRC1=CN2C(C=C1)=NC(/C=N/N(S(C3=CC([N+]([O-])=O)=CC=C3C)(=O)=O)C)=C2

IUPAC Name

2-Methyl-5-nitrobenzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide hydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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