JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120794

Pioglitazone hydrochloride, PPAR-gamma agonist

Be the first to review this product! Submit a review

|

(2 Publications)

MW 392.9 g/mol, Purity >99%. Selective PPAR-γ agonist (EC50 values are 280, >1000 and >1000 nM for PPAR isoforms γ, α and δ, respectively). Antidiabetic activities in vivo, improves the response to circulating insulin.
1 Images
Chemical Structure - Pioglitazone hydrochloride, PPAR-gamma agonist (AB120794)
  • Chemical Structure

Lab

Chemical Structure - Pioglitazone hydrochloride, PPAR-gamma agonist (AB120794)

2D chemical structure image of ab120794, Pioglitazone hydrochloride, PPAR-gamma agonist

Key facts

CAS number

112529-15-4

Purity

>99%

Form

Solid

form

Molecular weight

392.9 g/mol

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>0</sub>N<sub>2</sub>O<sub>3</sub>S.HCl

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Biological description

Selective PPAR-γ agonist (EC50 values are 280, >1000 and >1000 nM for PPAR isoforms γ, α and δ, respectively). Antidiabetic activities in vivo, improves the response to circulating insulin.

IUPAC Name

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride

style
left-column

Complementary Products

Primary Antibodies

AB207327

Anti-Albumin antibody [EPR20195]

RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Albumin antibody [EPR20195] (AB207327)

  • 5
  • 2
Assay Kits

AB133101

PPAR gamma Transcription Factor Assay Kit

Functional Studies - PPAR gamma Transcription Factor Assay Kit (AB133101)

  • 4
  • 3
Biochemicals

AB120876

T0070907, PPAR gamma antagonist

Chemical Structure - T0070907, PPAR gamma antagonist (AB120876)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 14:32087 PubMed39738433

2025

PPAR-γ agonist mitigates intestinal barrier dysfunction and inflammation induced by Clostridioides difficile SlpA in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Maryam Noori,Masoumeh Azimirad,Mahsa Ghorbaninejad,Anna Meyfour,Mohammad Reza Zali,Abbas Yadegar

Nature communications 7:13457 PubMed27892461

2016

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Stephen L Pinkosky,Roger S Newton,Emily A Day,Rebecca J Ford,Sarka Lhotak,Richard C Austin,Carolyn M Birch,Brennan K Smith,Sergey Filippov,Pieter H E Groot,Gregory R Steinberg,Narendra D Lalwani
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com