JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120153

Pirenzepine dihydrochloride, M1 antagonist

Be the first to review this product! Submit a review

|

(4 Publications)

MW 424.3 Da, Purity >98%. Selective M1 receptor antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
1 Images
Chemical Structure - Pirenzepine dihydrochloride, M1 antagonist (AB120153)
  • Chemical Structure

Lab

Chemical Structure - Pirenzepine dihydrochloride, M1 antagonist (AB120153)

2D chemical structure image of ab120153, Pirenzepine dihydrochloride, M1 antagonist

Key facts

CAS number

29868-97-1

Purity

>98%

Form

Solid

form

Molecular weight

424.3 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>3</sub>Cl<sub>2</sub>N<sub>5</sub>O<sub>2</sub>

PubChem

71405

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

Pirenzepine hydrochloride

Biological description

Selective M1 receptor antagonist.

Canonical smiles

CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl

InChi

InChI=1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H

InChiKey

FFNMBRCFFADNAO-UHFFFAOYSA-N

IUPAC Name

11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;dihydrochloride

style
left-column

Complementary Products

Proteins & Peptides

AB307187

Recombinant Mouse RANKL Protein (Active)

Premium Bioactive

Mass Spectrometry - Recombinant Mouse RANKL Protein (Active) (AB307187)

  • 0
  • 0
Biochemicals

AB146533

Acetosyringone, phenolic compound

Chemical Structure - Acetosyringone, phenolic compound (AB146533)

  • 0
  • 0
Proteins & Peptides

AB280753

Recombinant Human PD1 protein

Mass Spectrometry - Recombinant Human PD1 protein (AB280753)

  • 0
  • 0
Proteins & Peptides

AB50096

Recombinant mouse APRIL/TNFSF13 protein

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 5:3374 PubMed24594908

2014

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Neng-Wei Hu,Andrew J Nicoll,Dainan Zhang,Alexandra J Mably,Tiernan O'Malley,Silvia A Purro,Cassandra Terry,John Collinge,Dominic M Walsh,Michael J Rowan

Neuroscience letters 554:11-5 PubMed24012918

2013

Contribution of muscarinic M1 receptors to the cholinergic suppression of synaptic responses in layer II of the entorhinal cortex.

Applications

Unspecified application

Species

Unspecified reactive species

Shawnna G Barrett,C Andrew Chapman

Neuroscience 201:1-11 PubMed22138154

2011

Cholinergic suppression of excitatory synaptic transmission in layers II/III of the parasubiculum.

Applications

Unspecified application

Species

Unspecified reactive species

S D Glasgow,I Glovaci,L S Karpowicz,C A Chapman

Journal of neurophysiology 104:1841-8 PubMed20719927

2010

Endogenous inhibition of the trigeminally evoked neurotransmission to cardiac vagal neurons by muscarinic acetylcholine receptors.

Applications

Unspecified application

Species

Unspecified reactive species

C Gorini,K Philbin,R Bateman,D Mendelowitz
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com