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MW 185.22 Da, Purity >99%. Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.

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Chemical Structure - Pirfenidone, orally active anti-inflammatory antifibrotic agent (AB141425), expandable thumbnail

Publications

Key facts

CAS number
53179-13-8
Purity
> 99%
Form
Solid
Molecular weight
185.22 Da
Molecular formula
C12H11NO
PubChem identifier
40632
Nature
Synthetic

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MW 185.22 Da, Purity >99%. Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.

Key facts

Purity
> 99%
PubChem identifier
40632
Solubility

Soluble in 1 eq. HCl to 100 mM.

Soluble in water to 25 mM.

Biochemical name
Pirfenidone
Biological description

Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.

Canonical SMILES
CC1=CN(C(=O)C=C1)C2=CC=CC=C2
InChI
InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey
ISWRGOKTTBVCFA-UHFFFAOYSA-N
IUPAC name
5-methyl-1-phenylpyridin-2-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Pirfenidone, orally active anti-inflammatory antifibrotic agent (ab141425), expandable thumbnail

    Chemical Structure - Pirfenidone, orally active anti-inflammatory antifibrotic agent (ab141425)

    2D chemical structure image of ab141425, Pirfenidone, orally active anti-inflammatory antifibrotic agent

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Product protocols

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