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MW 420.48 g/mol, Purity >95%.

Negative control for clathrin inhibitor Pitstop® 1 (ab120685) which is of the same chemical class and has a highly related structure to Pitstop® 1. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).

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Images

Chemical Structure - Pitstop® 1 - negative control, Negative control for clathrin inhibitor Pitstop®1 (AB120686), expandable thumbnail

Publications

Key facts

Purity
> 95%
Form
Solid
Molecular weight
420.48 g/mol
Nature
Synthetic

Target data

Recommended products

MW 420.48 g/mol, Purity >95%.

Negative control for clathrin inhibitor Pitstop® 1 (ab120685) which is of the same chemical class and has a highly related structure to Pitstop® 1. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).

Key facts

Purity
> 95%
Solubility

Soluble in DMSO to 100mM.

Soluble in water to 25mM.

Biological description

Negative control for clathrin inhibitor Pitstop® 1 (ab120685) which is of the same chemical class and has a highly related structure to Pitstop® 1. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).

IUPAC name
2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-6-sulfonic acid potassium salt

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Notes

Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute.

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

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1 product image

  • Chemical Structure - Pitstop® 1 - negative control, Negative control for clathrin inhibitor Pitstop®1 (ab120686), expandable thumbnail

    Chemical Structure - Pitstop® 1 - negative control, Negative control for clathrin inhibitor Pitstop®1 (ab120686)

    2D chemical structure image of ab120686, Pitstop® 1 - negative control, Negative control for clathrin inhibitor Pitstop®1

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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