AB144650
Pitstop® 2-100, clathrin terminal domain inhibitor
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(2 Publications)
MW 463.35 g/mol, Purity >99%. Novel clathrin terminal domain inhibitor (IC50 = 7.5 μM). Specifically inhibits the internalisation of major histocompatibility complex 1 (MHC1). Related products Pitstop® 2 (ab120687), Pitstop® 1 (ab120686) and Pitstop® 1-25 (ab144651).
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- Chemical Structure
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Chemical Structure - Pitstop® 2-100, clathrin terminal domain inhibitor (AB144650)
2D chemical structure image of ab144650, Pitstop® 2-100, clathrin terminal domain inhibitor
Complementary Products
Product details
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute.
Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Publications (2)
Recent publications for all applications. Explore the full list and refine your search
Cellular & molecular immunology 20:264-276 PubMed36600053
2023
The neuropeptide CGRP enters the macrophage cytosol to suppress the NLRP3 inflammasome during pulmonary infection.
Applications
Unspecified application
Species
Unspecified reactive species
Fangrui Zhu,Dou Yu,Xiwen Qin,Yan Qian,Juan Ma,Weitao Li,Qiannv Liu,Chunlei Wang,Yan Zhang,Yi Li,Dong Jiang,Shuo Wang,Pengyan Xia
Molecular psychiatry : PubMed35484240
2022
Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy.
Applications
Unspecified application
Species
Unspecified reactive species
Abdel Ali Belaidi,Shashank Masaldan,Adam Southon,Pawel Kalinowski,Karla Acevedo,Ambili T Appukuttan,Stuart Portbury,Peng Lei,Puja Agarwal,Sue E Leurgans,Julie Schneider,Marcus Conrad,Ashley I Bush,Scott Ayton
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