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AB120161

PPT, subtype selective ERalpha agonist

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(1 Publication)

MW 386.44 g/mol, Purity >99%. Potent, subtype selective ERα estrogen receptor agonist. Over 400-fold selective for ERα over ERβ receptors.
1 Images
Chemical Structure - PPT, subtype selective ERalpha agonist (AB120161)
  • Chemical Structure

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Chemical Structure - PPT, subtype selective ERalpha agonist (AB120161)

2D chemical structure image of ab120161, PPT, subtype selective ERalpha agonist

Key facts

CAS number

263717-53-9

Purity

>99%

Form

Solid

form

Molecular weight

386.44 g/mol

Molecular formula

C<sub>2</sub><sub>4</sub>H<sub>2</sub><sub>2</sub>N<sub>2</sub>O<sub>3</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 5 mM

Biological description

Potent, subtype selective ERα estrogen receptor agonist. Over 400-fold selective for ERα over ERβ receptors.

Canonical smiles

OC1CCC(CC1)C3C(CCC)C(NN3C2CCC(O)CC2)C4CCC(O)CC4

InChi

InChI=1S/C24H22N2O3/c1-2-3-22-23(16-4-10-19(27)11-5-16)25-26(18-8-14-21(29)15-9-18)24(22)17-6-12-20(28)13-7-17/h4-15,27-29H,2-3H2,1H3

InChiKey

IOTXSIGGFRQYKW-UHFFFAOYSA-N

IUPAC Name

4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Acta ophthalmologica 103:571-579 PubMed39916676

2025

Neuroprotection of retinal ganglion cells by agonism of the beta but not the alpha oestrogen receptor in the axotomized retina of male and female mice.

Applications

Unspecified application

Species

Unspecified reactive species

Kristy T Rodríguez-Ramírez,Caridad Galindo-Romero,Fernando Lucas-Ruiz,Manuel Vidal-Sanz,Marta Agudo-Barriuso
View all publications

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