Skip to main content

MW 446.5 Da, Purity >98%. Potent, competitive HMG-CoA reductase inhibitor (IC50 = 95 nM). Biologically active metabolite of mevastatin (ab120652). Immunomodulator and cardiotropic agent. Active in vivo and in vitro. Water-soluble.

Be the first to review this product! Submit a review

Images

Chemical Structure - Pravastatin Sodium Salt, HMG-CoA reductase inhibitor (AB142617), expandable thumbnail

Key facts

CAS number
81131-70-6
Purity
> 98%
Form
Solid
Molecular weight
446.5 Da
Molecular formula
C23H35NaO7
PubChem identifier
16759173
Nature
Synthetic

Target data

Alternative names

3 hydroxy 3 methylglutaryl CoA reductase, 3 hydroxymethylglutaryl CoA reductase, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3H3M, HMDH_HUMAN, HMG CoAR, HMG-CoA reductase, Hydroxymethylglutaryl CoA reductase, LDLCQ3, MGC103269

Recommended products

MW 446.5 Da, Purity >98%. Potent, competitive HMG-CoA reductase inhibitor (IC50 = 95 nM). Biologically active metabolite of mevastatin (ab120652). Immunomodulator and cardiotropic agent. Active in vivo and in vitro. Water-soluble.

Key facts

Purity
> 98%
PubChem identifier
16759173
Solubility

Soluble in water.

Biochemical name
Pravastatin sodium
Biological description

Potent, competitive HMG-CoA reductase inhibitor (IC50 = 95 nM). Biologically active metabolite of mevastatin (ab120652). Immunomodulator and cardiotropic agent. Active in vivo and in vitro. Water-soluble.

Canonical SMILES
CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+]
Isomeric SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]
InChI
InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
InChIKey
VWBQYTRBTXKKOG-IYNICTALSA-M
IUPAC name
sodium;(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Pravastatin Sodium Salt, HMG-CoA reductase inhibitor (ab142617), expandable thumbnail

    Chemical Structure - Pravastatin Sodium Salt, HMG-CoA reductase inhibitor (ab142617)

    2D chemical structure image of ab142617, Pravastatin Sodium Salt, HMG-CoA reductase inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com