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MW 285.36 Da, Purity >98%. ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

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Images

Chemical Structure - Probenecid, ABC-transporter inhibitor (AB145725), expandable thumbnail

Publications

Key facts

CAS number
57-66-9
Purity
> 98%
Form
Solid
Molecular weight
285.36 Da
Molecular formula
C13H19NO4S
PubChem identifier
4911
Nature
Synthetic

Target data

Alternative names

CA 12, CA 2, CA-II, CA-IX, CA-XII, CA9, CAC, CAH12_HUMAN, CAH2_HUMAN, CAH9_HUMAN, Car 2, Carbonate dehydratase II, Carbonate dehydratase IX, Carbonate dehydratase XII, Carbonic anhydrase 12, Carbonic anhydrase 2, Carbonic anhydrase 9, Carbonic anhydrase B, Carbonic anhydrase C, Carbonic anhydrase C, formerly, Carbonic anhydrase II, Carbonic anhydrase IX, Carbonic anhydrase XII, Carbonic dehydratase, Epididymis secretory protein Li 282, FLJ20151, HEL-76, HEL-S-282, HsT18816, MN, Membrane antigen MN, P54/58N, RCC associated protein G250, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250, T18816, Tumor antigen HOM-RCC-3.1.3, epididymis luminal protein 76, pMW1

Recommended products

MW 285.36 Da, Purity >98%. ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

Key facts

Purity
> 98%
PubChem identifier
4911
Solubility

Soluble in ethanol to 75 mM.

Soluble in DMSO to 100 mM.

Biochemical name
Probenecid
Biological description

ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

Canonical SMILES
CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O
InChI
InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
InChIKey
DBABZHXKTCFAPX-UHFFFAOYSA-N
IUPAC name
4-(dipropylsulfamoyl)benzoic acid

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Probenecid, ABC-transporter inhibitor (ab145725), expandable thumbnail

    Chemical Structure - Probenecid, ABC-transporter inhibitor (ab145725)

    2D chemical structure image of ab145725, Probenecid, ABC-transporter inhibitor

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Product protocols

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