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AB145725

Probenecid, ABC-transporter inhibitor

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(1 Publication)

MW 285.36 Da, Purity >98%. ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.
1 Images
Chemical Structure - Probenecid, ABC-transporter inhibitor (AB145725)
  • Chemical Structure

Lab

Chemical Structure - Probenecid, ABC-transporter inhibitor (AB145725)

2D chemical structure image of ab145725, Probenecid, ABC-transporter inhibitor

Key facts

CAS number

57-66-9

Purity

>98%

Form

Solid

form

Molecular weight

285.36 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>9</sub>NO<sub>4</sub>S

PubChem

4911

Nature

Synthetic

Solubility

Soluble in ethanol to 75 mM

Soluble in DMSO to 100 mM

Biochemical name

Probenecid

Biological description

ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.

Canonical smiles

CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O

InChi

InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)

InChiKey

DBABZHXKTCFAPX-UHFFFAOYSA-N

IUPAC Name

4-(dipropylsulfamoyl)benzoic acid

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 22:3416-3426 PubMed29590612

2018

A Conserved Circadian Function for the Neurofibromatosis 1 Gene.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Bai,Yool Lee,Cynthia T Hsu,Julie A Williams,Daniel Cavanaugh,Xiangzhong Zheng,Carly Stein,Paula Haynes,Han Wang,David H Gutmann,Amita Sehgal
View all publications

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