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AB120888

Prostaglandin D2, HDP1 and CRTH2 receptor agonist

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MW 352.47 g/mol, Purity >99%. High affinity DP1 receptor agonist (Ki = 21 nM). Able to bind to the CRTH2 receptor (Ki = 2.4 nM). Major prostaglandin produced by mast cells in allergic disease. Capable of recruiting other inflammatory cells including eosinophils and basophils.

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1 Images
Chemical Structure - Prostaglandin D2, HDP1 and CRTH2 receptor agonist (AB120888)
  • Chemical Structure

Lab

Chemical Structure - Prostaglandin D2, HDP1 and CRTH2 receptor agonist (AB120888)

2D chemical structure image of ab120888, Prostaglandin D2, HDP1 and CRTH2 receptor agonist

Key facts

CAS number

41598-07-6

Purity

>99%

Form

Solid

form

Molecular weight

352.47 g/mol

Nature

Synthetic

Solubility

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biological description

High affinity DP1 receptor agonist (Ki = 21 nM). Able to bind to the CRTH2 receptor (Ki = 2.4 nM). Major prostaglandin produced by mast cells in allergic disease. Capable of recruiting other inflammatory cells including eosinophils and basophils.

Isomeric smiles

CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=CCCCC(=O)O

IUPAC Name

(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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