MW 388.9 Da, Purity >98%. Potent CDK inhibitor (IC50 = 100 nM for CDK2/cyclin A). Also inhibits other kinases in the low micromolar range, including DYRK1A and RSK1 (IC50 values are 0.3 and 1.49 μM, respectively).
(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, 1,8-cineole 2-exo-monooxygenase, AI327039, ARNT-interacting protein, Albendazole monooxygenase, Albendazole sulfoxidase, B cell CLL/lymphoma 1, B cell leukemia 1, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, Basic-helix-loop-helix-PAS protein MOP1, CCNA, CCNA1_HUMAN, CCNA2_HUMAN, CCNB, CCNB1_HUMAN, CCNB2_HUMAN, CCND1/FSTL3 fusion gene, CCND1/FSTL3 fusion gene, included, CCND1/IGHG1 fusion gene, CCND1/IGHG1 fusion gene, included, CCND1/IGLC1 fusion gene, CCND1/IGLC1 fusion gene, included, CCND1/PTH fusion gene, CCND1/PTH fusion gene, included, CCND1_HUMAN, CCNE, CCNE1_HUMAN, CCNE2 protein, CD1, CDC28A, CDK1_HUMAN, CDKN1, CELL CYCLE CONTROLLER CDC2, CP2C9_HUMAN, CP33, CP34, CP3A4_HUMAN, CPC9, CYC E2, CYP2C, CYP2C10, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIC9, CYPIIIA3, CYPIIIA4, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell division protein kinase 2, Cell division protein kinase 4, Cell division protein kinase 5, Cell division protein kinase 9, Class E basic helix-loop-helix protein 78, CycB2, Cyclin B1, Cyclin B2, Cyclin E1, Cyclin Es, Cyclin Et, Cyclin-A, Cyclin-A1, Cyclin-A2, Cyclin-dependent kinase 1, Cyclin-dependent kinase 4, Cyclin-dependent kinase 5, Cyclin-dependent kinase 9, CyclinE, CyclinE2, Cyl 1, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 NF-25, Cytochrome P450 PB-1, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450, family 2, subfamily C, polypeptide 9, Cytochrome P450-PCN1, D11S287E, DKFZp686L20222, G1/S specific cyclin E, G1/S specific cyclin E2, G1/S-specific cyclin-D1, G1/S-specific cyclin-E1, G2 mitotic specific cyclin B1, G2 mitotic specific cyclin B2, G2/mitotic specific cyclin A1, G2/mitotic specific cyclin B3, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin-B2, Glucocorticoid inducible P450, HIF-1, HIF-1-alpha, HIF-alpha, HIF1A_HUMAN, HLP, HsT17299, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Hypoxia inducible factor 1, alpha subunit (basic helix loop helix transcription factor), Hypoxia-inducible factor 1-alpha, IMD42, MGC108931, MGC111195, MGC126680, MGC129539, MGC132235, MGC140694, MGC149605, MGC159139, MGC88320, MOP 1, Member of PAS protein 1, Member of PAS superfamily 1, Member of the PAS Superfamily 1, Microsomal monooxygenase, NF 25, NR1F3, Nifedipine oxidase, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, OTTHUMP00000020135, P34CDC2, P450 III steroid inducible, P450 MP, P450 PB 1, P450 PCN1, P450, family III, P450C3, P450IIC9, PAS domain-containing protein 8, PASD 8, PRAD1, PRAD1 oncogene, Parathyroid adenomatosis 1, Quinine 3-monooxygenase, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RP11 805H4.3, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, S-mephenytoin 4-hydroxylase, TOR, Taurochenodeoxycholate 6-alpha-hydroxylase, U21B31, Xenobiotic monooxygenase, bHLHe78, cyclin E variant ex5del, cyclin E variant ex7del, cytochrome P-450 S-mephenytoin 4-hydroxylase, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, flavoprotein-linked monooxygenase, hifla, p33 protein kinase, p34 Cdk1, p34 protein kinase
MW 388.9 Da, Purity >98%. Potent CDK inhibitor (IC50 = 100 nM for CDK2/cyclin A). Also inhibits other kinases in the low micromolar range, including DYRK1A and RSK1 (IC50 values are 0.3 and 1.49 μM, respectively).
Soluble in DMSO to 100 mM.
Soluble in ethanol to 50 mM.
Potent CDK inhibitor (IC50 = 100 nM for CDK2/cyclin A). Also inhibits other kinases in the low micromolar range, including DYRK1A and RSK1 (IC50 values are 0.3 and 1.49 μM, respectively).
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2D chemical structure image of ab120304, Purvalanol A, CDK inhibitor
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