Purvalanol A, CDK inhibitor

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MW 388.9 Da, Purity >98%. Potent CDK inhibitor (IC₅₀ = 100 nM for CDK2/cyclin A). Also inhibits other kinases in the low micromolar range, including DYRK1A and RSK1 (IC₅₀ values are 0.3 and 1.49 μM, respectively).

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(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, 1,8-cineole 2-exo-monooxygenase, AI327039, ARNT-interacting protein, Albendazole monooxygenase, Albendazole sulfoxidase, B cell CLL/lymphoma 1, B cell leukemia 1, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, Basic-helix-loop-helix-PAS protein MOP1, CCNA, CCNA1_HUMAN, CCNA2_HUMAN, CCNB, CCNB1_HUMAN, CCNB2_HUMAN, CCND1/FSTL3 fusion gene, CCND1/FSTL3 fusion gene, included, CCND1/IGHG1 fusion gene, CCND1/IGHG1 fusion gene, included, CCND1/IGLC1 fusion gene, CCND1/IGLC1 fusion gene, included, CCND1/PTH fusion gene, CCND1/PTH fusion gene, included, CCND1_HUMAN, CCNE, CCNE1_HUMAN, CCNE2 protein, CD1, CDC28A, CDK1_HUMAN, CDKN1, CELL CYCLE CONTROLLER CDC2, CP2C9_HUMAN, CP33, CP34, CP3A4_HUMAN, CPC9, CYC E2, CYP2C, CYP2C10, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIC9, CYPIIIA3, CYPIIIA4, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell division protein kinase 2, Cell division protein kinase 4, Cell division protein kinase 5, Cell division protein kinase 9, Class E basic helix-loop-helix protein 78, CycB2, Cyclin B1, Cyclin B2, Cyclin E1, Cyclin Es, Cyclin Et, Cyclin-A, Cyclin-A1, Cyclin-A2, Cyclin-dependent kinase 1, Cyclin-dependent kinase 4, Cyclin-dependent kinase 5, Cyclin-dependent kinase 9, CyclinE, CyclinE2, Cyl 1, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 NF-25, Cytochrome P450 PB-1, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450, family 2, subfamily C, polypeptide 9, Cytochrome P450-PCN1, D11S287E, DKFZp686L20222, G1/S specific cyclin E, G1/S specific cyclin E2, G1/S-specific cyclin-D1, G1/S-specific cyclin-E1, G2 mitotic specific cyclin B1, G2 mitotic specific cyclin B2, G2/mitotic specific cyclin A1, G2/mitotic specific cyclin B3, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin-B2, Glucocorticoid inducible P450, HIF-1, HIF-1-alpha, HIF-alpha, HIF1A_HUMAN, HLP, HsT17299, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Hypoxia inducible factor 1, alpha subunit (basic helix loop helix transcription factor), Hypoxia-inducible factor 1-alpha, IMD42, MGC108931, MGC111195, MGC126680, MGC129539, MGC132235, MGC140694, MGC149605, MGC159139, MGC88320, MOP 1, Member of PAS protein 1, Member of PAS superfamily 1, Member of the PAS Superfamily 1, Microsomal monooxygenase, NF 25, NR1F3, Nifedipine oxidase, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, OTTHUMP00000020135, P34CDC2, P450 III steroid inducible, P450 MP, P450 PB 1, P450 PCN1, P450, family III, P450C3, P450IIC9, PAS domain-containing protein 8, PASD 8, PRAD1, PRAD1 oncogene, Parathyroid adenomatosis 1, Quinine 3-monooxygenase, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RP11 805H4.3, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, S-mephenytoin 4-hydroxylase, TOR, Taurochenodeoxycholate 6-alpha-hydroxylase, U21B31, Xenobiotic monooxygenase, bHLHe78, cyclin E variant ex5del, cyclin E variant ex7del, cytochrome P-450 S-mephenytoin 4-hydroxylase, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, flavoprotein-linked monooxygenase, hifla, p33 protein kinase, p34 Cdk1, p34 protein kinase