AB146140
PX 12, Thioredoxin-1 inhibitor
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MW 188.3 Da, Purity >98%. Irreversible, competitive Thioredoxin-1 inhibitor (Ki = 30.8 μM). Attenuates HIF-1α, VEGF and iNOS expression (IC50 values are 7.2, 10.4 and 18.1 μM, respectively). Inhibits tubulin and decreases tumor blood vessel density. Shows antitumor effects in vivo..
1 Images
- Chemical Structure
Lab
Chemical Structure - PX 12, Thioredoxin-1 inhibitor (AB146140)
2D chemical structure image of ab146140, PX 12, Thioredoxin-1 inhibitor
Product details
This product is manufactured by BioVision, an Abcam company and was previously called 2217 PX 12. 2217-25 is the same size as the 25 mg size of ab146140.
Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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