MW 371.3 Da, Purity >98%. Ubiquitin-activating enzyme (E1) inhibitor (IC50 = 5 μM). Inhibits ubiquitination and proteasomal degradation. Additionally increases sumoylation of proteins and induces p53-mediated apoptosis.
418805-02-4
> 98%
Solid
371.3 Da
C17H13N3O7
5335621
Synthetic
MW 371.3 Da, Purity >98%. Ubiquitin-activating enzyme (E1) inhibitor (IC50 = 5 μM). Inhibits ubiquitination and proteasomal degradation. Additionally increases sumoylation of proteins and induces p53-mediated apoptosis.
418805-02-4
> 98%
Solid
371.3 Da
C17H13N3O7
5335621
Synthetic
Soluble in DMSO to 50 mM.
Pyr-41
Ubiquitin-activating enzyme (E1) inhibitor (IC50 = 5 μM). Inhibits ubiquitination and proteasomal degradation. Additionally increases sumoylation of proteins and induces p53-mediated apoptosis.
CCOC(=O)C1=CC=C(C=C1)N2C(=O)C(=CC3=CC=C(O3)[N+](=O)[O-])C(=O)N2
CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2
InChI=1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21)/b13-9-
ARGIPZKQJGFSGQ-LCYFTJDESA-N
ethyl 4-[(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl]benzoate
Ambient - Can Ship with Ice
-20°C
-20°C
Store under desiccating conditions, The product can be stored for up to 12 months
This product is manufactured by BioVision, an Abcam company and was previously called 1925 PYR-41. 1925-25 is the same size as the 25 mg size of ab141469.
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2D chemical structure image of ab141469, PYR-41, Ubiquitin-activating enzyme (E1) inhibitor
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