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MW 286.29 Da, Purity >99%. Cell-permeable non-toxic hydrazone iron chelator. Prevents iron-mediated oxyradical formation and minimizes tissue damage. Anticancer and apoptotic agent. Active in vitro.

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Chemical Structure - Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator (AB145871), expandable thumbnail

Publications

Key facts

CAS number
737-86-0
Purity
> 99%
Form
Solid
Molecular weight
286.29 Da
Molecular formula
C14H14N4O3
PubChem identifier
135409539
Nature
Synthetic

Target data

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MW 286.29 Da, Purity >99%. Cell-permeable non-toxic hydrazone iron chelator. Prevents iron-mediated oxyradical formation and minimizes tissue damage. Anticancer and apoptotic agent. Active in vitro.

See similar compounds.

Key facts

Purity
> 99%
PubChem identifier
135409539
Solubility

Soluble in DMSO to 100 mM.

Biochemical name
Pyridoxal isonicotinoyl hydrazone
Biological description

Cell-permeable non-toxic hydrazone iron chelator. Prevents iron-mediated oxyradical formation and minimizes tissue damage. Anticancer and apoptotic agent. Active in vitro.

See similar compounds

Canonical SMILES
CC1=NC=C(C(=C1O)C=NNC(=O)C2=CC=NC=C2)CO
Isomeric SMILES
CC1=NC=C(C(=C1O)/C=N/NC(=O)C2=CC=NC=C2)CO
InChI
InChI=1S/C14H14N4O3/c1-9-13(20)12(11(8-19)6-16-9)7-17-18-14(21)10-2-4-15-5-3-10/h2-7,19-20H,8H2,1H3,(H,18,21)/b17-7+
InChIKey
BQYIXOPJPLGCRZ-REZTVBANSA-N
IUPAC name
N-[(E)-[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methylideneamino]pyridine-4-carboxamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions

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1 product image

  • Chemical Structure - Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator (ab145871), expandable thumbnail

    Chemical Structure - Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator (ab145871)

    2D chemical structure image of ab145871, Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator

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Product protocols

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