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AB120247

Quercetin, Antioxidative flavonoid

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(3 Publications)

MW 302.23 Da, Purity >97%. Antioxidative flavonoid. Anticancer, antithrombotic and anti-inflammatory agent. Actions include inhibition of mitochondrial ATPase, phosphodiesterases, PI3-kinase and PIP kinase activity.
2 Images
Functional Studies - Quercetin, Antioxidative flavonoid (AB120247)
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Functional Studies - Quercetin, Antioxidative flavonoid (AB120247)

ab13847 staining active caspase 3 in A549 cells treated with quercetin (ab120247), by ICC/IF. Increase in active caspase 3 expression correlates with increased concentration of quercetin, as described in literature.
The cells were incubated at 37°C for 6h in media containing different concentrations of ab120247 (quercetin) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab13847 (1 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight® 488 goat anti-rabbit polyclonal antibody (ab968999) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

Chemical Structure - Quercetin, Antioxidative flavonoid (AB120247)
  • Chemical Structure

Lab

Chemical Structure - Quercetin, Antioxidative flavonoid (AB120247)

2D chemical structure image of ab120247, Quercetin, Antioxidative flavonoid

Key facts

CAS number

117-39-5

Purity

>97%

Form

Solid

form

Molecular weight

302.23 Da

Molecular formula

C<sub>1</sub><sub>5</sub>H<sub>1</sub><sub>0</sub>O<sub>7</sub>

PubChem

5280343

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

Quercetin

Biological description

Antioxidative flavonoid. Anticancer, antithrombotic and anti-inflammatory agent. Actions include inhibition of mitochondrial ATPase, phosphodiesterases, PI3-kinase and PIP kinase activity.

Canonical smiles

C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

InChi

InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H

InChiKey

REFJWTPEDVJJIY-UHFFFAOYSA-N

IUPAC Name

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20:36 PubMed40220083

2025

Antioxidant-Effective Quercetin Through Modulation of Brain Interleukin-13 Mitigates Autistic-Like Behaviors in the Propionic Acid-Induced Autism Model in Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Kubilay Doğan Kılıç,Gökçen Garipoğlu,Burak Çakar,Yiğit Uyanıkgil,Oytun Erbaş

Phytomedicine : international journal of phytother 58:152893 PubMed30901663

2019

Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ying-Ju Lin,Wen-Miin Liang,Chao-Jung Chen,Hsinyi Tsang,Jian-Shiun Chiou,Xiang Liu,Chi-Fung Cheng,Ting-Hsu Lin,Chiu-Chu Liao,Shao-Mei Huang,Jianxin Chen,Fuu-Jen Tsai,Te-Mao Li

Scientific reports 7:2262 PubMed28536445

2017

Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.

Applications

Unspecified application

Species

Unspecified reactive species

Kaoru Ishida,Chie Ito,Yukimi Ohmori,Kohei Kume,Kei A Sato,Yuka Koizumi,Akari Konta,Takeshi Iwaya,Mamoru Nukatsuka,Takashi Kobunai,Teiji Takechi,Satoshi S Nishizuka
View all publications
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