JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB144639

Quinol 1h, Antitumor agent

Be the first to review this product! Submit a review

|

(0 Publication)

MW 365.4 Da, Purity >99%. Potent, selective antitumor agent. Antitumor activity observed in HCT 116 (GI50 = 40 nM) and HT 29 (GI50 = 380 nM), and in breast cancer cell lines. Potent inhibitory effect in NCI 60 cells (GI50 =16 nM and LC50 = 2.24 μM). Active in vitro.
1 Images
Chemical Structure - Quinol 1h, Antitumor agent (AB144639)
  • Chemical Structure

Lab

Chemical Structure - Quinol 1h, Antitumor agent (AB144639)

2D chemical structure image of ab144639, Quinol 1h, Antitumor agent

Key facts

CAS number

719308-90-4

Purity

>99%

Form

Solid

form

Molecular weight

365.4 Da

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>5</sub>NO<sub>4</sub>S

PubChem

9907134

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

1H-Indole, 2-(1-hydroxy-4-oxo-2,5-cyclohexadien-1-yl)-1-(phenylsulfonyl)-

Biological description

Potent, selective antitumor agent. Antitumor activity observed in HCT 116 (GI50 = 40 nM) and HT 29 (GI50 = 380 nM), and in breast cancer cell lines. Potent inhibitory effect in NCI 60 cells (GI50 =16 nM and LC50 = 2.24 μM). Active in vitro.

Canonical smiles

C1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3C=C2C4(C=CC(=O)C=C4)O

InChi

InChI=1S/C20H15NO4S/c22-16-10-12-20(23,13-11-16)19-14-15-6-4-5-9-18(15)21(19)26(24,25)17-7-2-1-3-8-17/h1-14,23H

InChiKey

HWKQYGBAAMKHDY-UHFFFAOYSA-N

IUPAC Name

4-[1-(benzenesulfonyl)indol-2-yl]-4-hydroxycyclohexa-2,5-dien-1-one

style
left-column

Complementary Products

Proteins & Peptides

AB183223

Recombinant Human PACT (PKR activating protein) / PRKRA (His tag N-Terminus)

SDS-PAGE - Recombinant Human PACT (PKR activating protein) / PRKRA (His tag N-Terminus) (AB183223)

  • 0
  • 0
Proteins & Peptides

AB183171

Recombinant Human Paralemmin-1 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Paralemmin-1 protein (His tag N-Terminus) (AB183171)

  • 0
  • 0
Biochemicals

AB144640

Quinol 2, Antitumor agent

Chemical Structure - Quinol 2, Antitumor agent (AB144640)

  • 0
  • 0
Biochemicals

AB141128

VUF8430 dihydrobromide, H4 receptor agonist

Chemical Structure - VUF8430 dihydrobromide, H4 receptor agonist (AB141128)

  • 0
  • 0
style
left-column

Product details

Sold under license from CRT.
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com