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AB144640

Quinol 2, Antitumor agent

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MW 243.28 Da, Purity >99%. Selective antitumor agent. Active against colon, renal and breast carcinomas in vitro and ex vivo. Inhibits thioredoxin reductase with potencies correlated with antiproliferative and cytotoxic effects. Potent inhibitory effect in NCI 60 cells (GI50 =0.23 μM and LC50 = 3.39 μM).
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Chemical Structure - Quinol 2, Antitumor agent (AB144640)
  • Chemical Structure

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Chemical Structure - Quinol 2, Antitumor agent (AB144640)

2D chemical structure image of ab144640, Quinol 2, Antitumor agent

Key facts

CAS number

485842-97-5

Purity

>99%

Form

Solid

form

Molecular weight

243.28 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>9</sub>NO<sub>2</sub>S

PubChem

482697

Nature

Synthetic

Solubility

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

4-(Benzothiazol-2-yl)-4-hydroxy-2,5-cyclohexadien-1-one

Biological description

Selective antitumor agent. Active against colon, renal and breast carcinomas in vitro and ex vivo. Inhibits thioredoxin reductase with potencies correlated with antiproliferative and cytotoxic effects. Potent inhibitory effect in NCI 60 cells (GI50 =0.23 μM and LC50 = 3.39 μM).

Canonical smiles

C1=CC=C2C(=C1)N=C(S2)C3(C=CC(=O)C=C3)O

InChi

InChI=1S/C13H9NO2S/c15-9-5-7-13(16,8-6-9)12-14-10-3-1-2-4-11(10)17-12/h1-8,16H

InChiKey

SDYBYKXWYDVVKP-UHFFFAOYSA-N

IUPAC Name

4-(1,3-benzothiazol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-one

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Product details

Sold under license from CRT.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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