Quisqualic acid (mM/ml), group I mGlu agonist
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MW 189.13 Da, Purity >99%. Potent group I mGlu agonist and AMPA receptor agonist. Achieve your results faster with highly validated, pure and trusted compounds.
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AMPA 1, AMPA 2, AMPA 3, AMPA 4, AMPA-selective glutamate receptor 1, AMPA-selective glutamate receptor 2, AMPA-selective glutamate receptor 3, AMPA-selective glutamate receptor 4, EEA3, Excitatory amino acid receptor 1, Excitatory amino acid receptor 2, Excitatory amino acid receptor 3, Excitatory amino acid receptor 4, Excitatory amino acid receptor 5, GLR 6, GLR 7, GLR5, GLUH1, GLUK3, GLUK6, GLUR, GLUR4C, GPRC1A, GPRC1E, GRIA1_HUMAN, GRIA2_HUMAN, GRIA3_HUMAN, GRIA4_HUMAN, GRIK, GRIK1_HUMAN, GRIK2 protein, GRIK2_HUMAN, GRIK3_HUMAN, GRIK4_HUMAN, GRIK5_HUMAN, GRM1-Alpha, GRM1_HUMAN, GRM5_HUMAN, GluA 4, GluA1, GluA2, GluA3, GluK2, GluK4, GluK5, GluR 7a, GluR-1, GluR-2, GluR-3, GluR-4, GluR-5, GluR-6, GluR-7, GluR-A, GluR-B, GluR-C, GluR-D, GluR-K1, GluR-K2, GluR-K3, GluRgamma2, Glutamate ionotropic receptor AMPA type subunit 3, Glutamate receptor, Glutamate receptor 1, Glutamate receptor 2, Glutamate receptor 3, Glutamate receptor 4, Glutamate receptor 5, Glutamate receptor 6, Glutamate receptor 7, Glutamate receptor C, Glutamate receptor KA 1precursor, Glutamate receptor KA-1, Glutamate receptor KA-2, Glutamate receptor ionotrophic AMPA 3, Glutamate receptor ionotrophic AMPA 4, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic AMPA 2, Glutamate receptor ionotropic kainate 1, Glutamate receptor ionotropic kainate 2, Glutamate receptor ionotropic kainate 3, Glutamate receptor ionotropic kainate 4, Glutamate receptor ionotropic kainate 4 precursor, Glutamate receptor metabotropic 1, Glutamate receptor metabotropic 5, Glutamate receptor subunit 3, Glutamate receptor, ionotropic kainate 5 [Precursor], Glutamate receptor, ionotropic, AMPA 3, Glutamate receptor, ionotropic, kainate 5, Glutamate receptor, ionotropic, kainate 5 (gamma 2), HBGR1, HBGR2, Human glutamate receptor GLUR5, Ionotrophic Glutamate Receptor, Ionotropic Glutamate receptor 4, KA2, MGC118086, MGC133252, MGLU1, MRT6, MRX94, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, OTTHUMP00000045951, OTTHUMP00000096569, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, OTTHUMP00000231881, PPP1R86, Protein phosphatase 1 regulatory subunit 86, SCAR13, Smp_128940, bA487F5.1, dJ1171F9.1, glutamate receptor form A, glutamate receptor form B, glutamate receptor form C, glutamate receptor form D, glutamate receptor form E, iGlu5, ionotropic kainate 1, ionotropic kainate 2, ionotropic kainate 3, ionotropic kainate 4, ionotropic kainate 5, mGlu5, mGluR1, mGluR5
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Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
These receptors drive important processes in neurocommunication and plasticity. They act in both ionotropic capacity mediating fast excitatory transmission through cation flows and metabotropic roles modulating signalling pathways via G-proteins. Receivers like GluA1 form tetrameric complexes facilitating synaptic responses and are important in learning and memory. Metabotropic variants such as mGluR1a and mGluR5 influence synaptic plasticity and development by modulating intracellular signalling cascades. Together these receptors are essential in transmitting the excitatory signals important for normal brain function.
Pathways
These receptors are integral to pathways such as the glutamatergic synapse and neurotrophin signalling pathways. They interact with proteins such as PSD-95 within postsynaptic density where AMPA and NMDA receptors play a synergistic role in synaptic strength. Their interaction allows the fine-tuning of synaptic responses. The Metabotropic receptors are linked to intracellular pathways impacting calcium signalling while the Kainate receptors contribute to the regulation of excitability and neurotransmitter release.
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