(R)-(+)-Etomoxir, CPT1 inhibitor

Key facts

CAS number

124083-20-1

Purity

>98%

Form

Solid

form

Molecular weight

326.8 Da

Molecular formula

C₁₇H₂₃ClO₄

PubChem

9840324

Nature

Synthetic

Solubility

Soluble in water to 20 mM

Soluble in DMSO to 20 mM (with gentle warming)

Biochemical name

R-(+)-Etomoxir

Biological description

CPT1 inhibitor. Inhibits β-oxidation in mitochondria (IC₅₀ values are 0.1, 1 and 10 μM for human, guinea pig and rat hepatocytes respectively). Putative antidiabetic agent.

Canonical smiles

CCOC(=O)C1(CO1)CCCCCCOC2=CC=C(C=C2)Cl

Isomeric smiles

CCOC(=O)[C@]1(CO1)CCCCCCOC2=CC=C(C=C2)Cl

InChi

InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1

InChiKey

DZLOHEOHWICNIL-QGZVFWFLSA-N

IUPAC Name

ethyl (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate