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AB120761

(R)-(-)-Phenylephrine hydrochloride, alpha1 Adrenoceptor agonist

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(5 Publications)

MW 203.67 g/mol, Purity >99%. α1 Adrenoceptor agonist. pKi values are 4.87, 4.70 and 5.86 for adrenoceptor subtypes α1B, α1C and α1A/D, respectively. Vasoconstrictor. Active in vivo, may cross the blood-brain barrier.
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Chemical Structure - (R)-(-)-Phenylephrine hydrochloride, alpha1 Adrenoceptor agonist (AB120761)
  • Chemical Structure

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Chemical Structure - (R)-(-)-Phenylephrine hydrochloride, alpha1 Adrenoceptor agonist (AB120761)

2D chemical structure image of ab120761, (R)-(-)-Phenylephrine hydrochloride, alpha1 Adrenoceptor agonist

Key facts

CAS number

61-76-7

Purity

>99%

Form

Solid

form

Molecular weight

203.67 g/mol

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

Biological description

α1 Adrenoceptor agonist. pKi values are 4.87, 4.70 and 5.86 for adrenoceptor subtypes α1B, α1C and α1A/D, respectively. Vasoconstrictor. Active in vivo, may cross the blood-brain barrier.

IUPAC Name

(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cardiovascular medicine 10:1137429 PubMed37404738

2023

Identify Tcea3 as a novel anti-cardiomyocyte hypertrophy gene involved in fatty acid oxidation and oxidative stress.

Applications

Unspecified application

Species

Unspecified reactive species

Yingying Guo,Xian-Feng Cen,Dan Li,Hong-Liang Qiu,Ya-Jie Chen,Meng Zhang,Si-Hui Huang,Hao Xia,Man Xu

International journal of molecular sciences 19: PubMed30469522

2018

Noradrenaline Sensitivity Is Severely Impaired in Immortalized Adipose-Derived Mesenchymal Stem Cell Line.

Applications

Unspecified application

Species

Unspecified reactive species

Pyotr A Tyurin-Kuzmin,Vadim I Chechekhin,Anastasiya M Ivanova,Daniyar T Dyikanov,Veronika Y Sysoeva,Natalia I Kalinina,Vsevolod A Tkachuk

Scientific reports 6:32835 PubMed27596381

2016

Activation of β-adrenergic receptors is required for elevated α1A-adrenoreceptors expression and signaling in mesenchymal stromal cells.

Applications

Unspecified application

Species

Unspecified reactive species

Pyotr A Tyurin-Kuzmin,Julia I Fadeeva,Margarita A Kanareikina,Natalia I Kalinina,Veronika Yu Sysoeva,Daniyar T Dyikanov,Dmitriy V Stambolsky,Vsevolod A Tkachuk

American journal of translational research 8:37-48 PubMed27069538

2016

The potential role of lysosome-associated membrane protein 3 (LAMP3) on cardiac remodelling.

Applications

Unspecified application

Species

Unspecified reactive species

Ding-Sheng Jiang,Xin Yi,Bo Huo,Xin-Xin Liu,Rui Li,Xue-Hai Zhu,Xiang Wei

Neuropharmacology 89:33-42 PubMed25218865

2014

Noradrenergic modulation of the parallel fiber-Purkinje cell synapse in mouse cerebellum.

Applications

Unspecified application

Species

Unspecified reactive species

Pellegrino Lippiello,Eriola Hoxha,Floriana Volpicelli,Giuseppina Lo Duca,Filippo Tempia,Maria Concetta Miniaci
View all publications
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