Radicicol, Heat shock protein (HSP) 90 inhibitor

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MW 364.8 Da, Purity >99%. Heat shock protein 90 inhibitor and antifungal antibiotic. Binds to the N-terminal ATP/ADP-binding domain suppressing cell transformation induced by src, ras and mos. Induces cell cycle arrest at G₁-S phase. Shows antiangiogenic effects in vivo.

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15-hydroxyprostaglandin dehydrogenase [NADP+], 90 kda heat shock protein beta HSP90 beta, ASV, AW259666, Avian sarcoma virus, C SRC, CBR1_HUMAN, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA, CRN, Carbonyl Reductase 1, Carbonyl reductase [NADPH] 1, Cyclooxygenase, Cyclooxygenase 2b, Cyclooxygenase-2, D6S182, EC 1.14.99.1, EC 2.7.10.2, FLJ26984, GRIPGHS, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, Glucocorticoid-regulated inflammatory cyclooxygenase, HS90A_HUMAN, HS90B_HUMAN, HSP 84, HSP 86, HSP 90, HSP 90 b, HSP90 BETA, HSP90A, HSP90AA1, HSP90AB1, HSPC1, HSPC2, HSPCAL1, HSPCAL4, HSPCB, Heat shock 84 kDa, Heat shock 86 kDa, Heat shock 90kD protein 1, beta, Heat shock 90kDa protein 1 beta, Heat shock protein 90 alpha family class B member 1, Heat shock protein 90 kDa, Heat shock protein 90kDa alpha (cytosolic) class B member 1, Heat shock protein 90kDa alpha cytosolic class A member 1, Heat shock protein 90kDa alpha cytosolic class B member 1, Heat shock protein 90kDa alpha family class B member 1, Heat shock protein HSP 90-alpha, Heat shock protein HSP 90-beta, Heat shock protein beta, Macrophage activation-associated marker protein P71/73, NADPH-dependent carbonyl reductase 1, Neuronal CSRC tyrosine specific protein kinase, Neuronal SRC, Neuronal proto-oncogene tyrosine-protein kinase Src, OTTHUMP00000033524, OTTHUMP00000174476, OTTHUMP00000174477, Oncogene SRC, PES-2, PGG/HS, PGH synthase 2, PGH2_HUMAN, PGHS-2, PHS 2, PHS II, PTGS2, Prostaglandin 9-ketoreductase, Prostaglandin G/H synthase, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 2 precursor, Prostaglandin G/H synthase and cyclooxygenase, Prostaglandin H2 synthase 2, Prostaglandin-E(2) 9-reductase, Prostaglandin-endoperoxide synthase 2, Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, Protooncogene SRC, Protooncogene SRC Rous sarcoma, Renal carcinoma antigen NY-REN-38, SDR21C1, SRC Oncogene, SRC proto oncogene non receptor tyrosine kinase, SRC_HUMAN, TIS10, TIS10 protein, Tyrosine kinase pp60c src, Tyrosine protein kinase SRC 1, V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian), fj02a10, hCox 2, p60-Src, p60c-src, pp60c-src, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), ptgs2a, unp1239, v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog, v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian, wu:fj02a10