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AB142942

Ranolazine dihydrochloride, Anti-ischemic agent

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MW 500.5 Da, Purity >99%. Novel metabolic modulator and membrane stabilizer. Partial fatty acid oxidation inhibitor. Pyruvate dehydrogenase activator. Shifts myocardial energy metabolism towards glucose for ATP production. Inhibits late INa and IKr currents. Anti-ischemic effects in vivo. .
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Chemical Structure - Ranolazine dihydrochloride, Anti-ischemic agent (AB142942)
  • Chemical Structure

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Chemical Structure - Ranolazine dihydrochloride, Anti-ischemic agent (AB142942)

2D chemical structure image of ab142942, Ranolazine dihydrochloride, Anti-ischemic agent

Key facts

CAS number

95635-56-6

Purity

>99%

Form

Solid

form

Molecular weight

500.5 Da

Molecular formula

C<sub>2</sub><sub>4</sub>H<sub>3</sub><sub>5</sub>Cl<sub>2</sub>N<sub>3</sub>O<sub>4</sub>

PubChem

71279

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

Ranolazine dihydrochloride

Biological description

Novel metabolic modulator and membrane stabilizer. Partial fatty acid oxidation inhibitor. Pyruvate dehydrogenase activator. Shifts myocardial energy metabolism towards glucose for ATP production. Inhibits late INa and IKr currents. Anti-ischemic effects in vivo.

Canonical smiles

CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl

InChi

InChI=1S/C24H33N3O4.2ClH/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3;;/h4-10,20,28H,11-17H2,1-3H3,(H,25,29);2*1H

InChiKey

RJNSNFZXAZXOFX-UHFFFAOYSA-N

IUPAC Name

N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide;dihydrochloride

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Complementary Products

Biochemicals

AB120739

Trifluoperazine dihydrochloride, calmodulin antagonist

Chemical Structure - Trifluoperazine dihydrochloride, calmodulin antagonist (AB120739)

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Biochemicals

AB120535

Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist

Chemical Structure - Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist (AB120535)

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Primary Antibodies

AB307442

Anti-TLR3 antibody [EPR27050-89]

20ul selling size|RabMAb|Recombinant

Western blot - Anti-TLR3 antibody [EPR27050-89] (AB307442)

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Primary Antibodies

AB184699

Anti-ERK1 + ERK2 antibody [EPR17526]

RabMAb|Recombinant|KO Validated

Immunocytochemistry - Anti-ERK1 + ERK2 antibody [EPR17526] (AB184699)

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  • 1
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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