MW 394.5 Da, Purity >98%. Selective diacylglycerol lipase inhibitor (IC50 = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro.
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- European journal of pharmacology 517:97-1022005The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPhilippe Ghisdal,Greet Vandenberg,Marie-Christine Hamaide,Maurice Wibo,Nicole MorelPubMed 15958263
- Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 38:153-642003Effects of RHC-80267, an inhibitor of diacylglycerol lipase, on excitation of circular smooth muscle of the guinea-pig gastric antrum.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHikaru Suzuki,Yoshihiko Kito,Hiroyasu Fukuta,Yoshimichi YamamotoPubMed 12713022
- The Journal of biological chemistry 257:14006-101982Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267.Applications:Unspecified applicationReactive species:Unspecified reactive speciesC A Sutherland,D AminPubMed 7142192
Key facts
- CAS number
83654-05-1
- Purity
> 98%
- Molecular weight
394.5 Da
- Molecular formula
C20H34N4O4
- PubChem identifier
5063
- Nature
Synthetic
Alternative names
C11orf11, Chromosome 11 open reading frame 11, DAGL(ALPHA), DAGLALPHA, DAGLBETA, DGL-alpha, DGL-beta, DGLA_HUMAN, DGLB_HUMAN, Diacylglycerol lipase alpha, Diacylglycerol lipase beta, KCCR13L, KIAA0659, NSDDR, Neural stem cell-derived dendrite regulator, Sn1-specific diacylglycerol lipase alpha, Sn1-specific diacylglycerol lipase beta
Recommended products
MW 394.5 Da, Purity >98%. Selective diacylglycerol lipase inhibitor (IC50 = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro.
Alternative names
C11orf11, Chromosome 11 open reading frame 11, DAGL(ALPHA), DAGLALPHA, DAGLBETA, DGL-alpha, DGL-beta, DGLA_HUMAN, DGLB_HUMAN, Diacylglycerol lipase alpha, Diacylglycerol lipase beta, KCCR13L, KIAA0659, NSDDR, Neural stem cell-derived dendrite regulator, Sn1-specific diacylglycerol lipase alpha, Sn1-specific diacylglycerol lipase beta
Key facts
- CAS number
83654-05-1
- Purity
> 98%
- Molecular weight
394.5 Da
- Molecular formula
C20H34N4O4
- PubChem identifier
5063
- Nature
Synthetic
- Solubility
Soluble in DMSO to 50 mM. Soluble in ethanol to 50 mM.
- Biochemical name
1,6-Bis(cyclohexyloximinocarbonyl)hexane
- Biological description
Selective diacylglycerol lipase inhibitor (IC50 = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro.
- Canonical SMILES
C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
- InChI
InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
- InChIKey
RXSVYGIGWRDVQC-UHFFFAOYSA-N
- IUPAC name
(cyclohexylideneamino) N-[6-[(cyclohexylideneamino)oxycarbonylamino]hexyl]carbamate
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
Ambient
- Appropriate long-term storage conditions
Ambient
- Storage information
The product can be stored for up to 12 months
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1 product image
Chemical Structure - RHC-80267, diacylglycerol lipase inhibitor (ab141758)
2D chemical structure image of ab141758, RHC-80267, diacylglycerol lipase inhibitor
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