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AB275545

Rhodamine 123

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(3 Publications)

MW 380.8 Da, Purity >98%. Cell-permeable, green fluorescent dye suitable for monitoring membrane polarization in mitochondria and bacteria in live cell assays. Accumulation in membranes is dependent on membrane polarization. Also used in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA. Absorption peak at 505 nm. Luminescence tunable at ~560 nm when used as a laser dye.
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Chemical Structure - Rhodamine 123 (AB275545)
  • Chemical Structure

Lab

Chemical Structure - Rhodamine 123 (AB275545)

Chemical structure of Rhodamine 123, 62669-70-9

Key facts

CAS number

62669-70-9

Purity

>98%

Form

Solid

form

Molecular weight

380.8 Da

Molecular formula

C<sub>2</sub><sub>1</sub>H<sub>1</sub><sub>7</sub>ClN<sub>2</sub>O<sub>3</sub>

PubChem

9929799

Nature

Synthetic

Solubility

Soluble in DMSO.

Biochemical name

Rhodamine 123

Biological description

Cell-permeable, green fluorescent dye suitable for monitoring membrane polarization in mitochondria and bacteria in live cell assays. Accumulation in membranes is dependent on membrane polarization. Also used in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA. Absorption peak at 505 nm. Luminescence tunable at ~560 nm when used as a laser dye.

Canonical smiles

COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N.Cl

InChi

InChI=1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H

InChiKey

MYFATKRONKHHQL-UHFFFAOYSA-N

IUPAC Name

methyl 2-(3-amino-6-iminoxanthen-9-yl)benzoate;hydrochloride

Excitation/Emission

Ex: 505nm, Em: 534nm

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 14:1338802 PubMed38347844

2024

Aluminium phthalocyanine-mediated photodynamic therapy induces ATM-related DNA damage response and apoptosis in human oesophageal cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Onyisi Christiana Didamson,Rahul Chandran,Heidi Abrahamse

PloS one 17:e0274704 PubMed36480501

2022

HAPLN1 confers multiple myeloma cell resistance to several classes of therapeutic drugs.

Applications

Unspecified application

Species

Unspecified reactive species

Mailee Huynh,Hae Yeun Chang,Dominique N Lisiero,Irene M Ong,Trinayan Kashyap,Natalie S Callander,Shigeki Miyamoto

EMBO molecular medicine 14:e14903 PubMed35023619

2022

Inhibition of NPC1L1 disrupts adaptive responses of drug-tolerant persister cells to chemotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Zhe Zhang,Siyuan Qin,Yan Chen,Li Zhou,Mei Yang,Yongquan Tang,Jing Zuo,Jian Zhang,Atsushi Mizokami,Edouard C Nice,Hai-Ning Chen,Canhua Huang,Xiawei Wei
View all publications
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