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AB120601

Rotigotine hydrochloride, Dopamine receptor agonist

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MW 351.93 g/mol, Purity >99%. Dopamine receptor agonist. High affinity for D1, D2 and D3 receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α2B and 5-HT1A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.
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Chemical Structure - Rotigotine hydrochloride, Dopamine receptor agonist (AB120601)
  • Chemical Structure

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Chemical Structure - Rotigotine hydrochloride, Dopamine receptor agonist (AB120601)

2D chemical structure image of ab120601, Rotigotine hydrochloride, Dopamine receptor agonist

Key facts

CAS number

125572-93-2

Purity

>99%

Form

Solid

form

Molecular weight

351.93 g/mol

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>5</sub>NOS.HCl

Nature

Synthetic

Solubility

Soluble in water to 10 mM (with warming

Soluble in DMSO to 100 mM

Biological description

Dopamine receptor agonist. High affinity for D1, D2 and D3 receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α2B and 5-HT1A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.

IUPAC Name

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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