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AB120149

(R,S)-Baclofen, GABAB agonist

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(3 Publications)

MW 213.66 Da, Purity >99%. Selective GABAB receptor agonist. Antispasmodic. Achieve your results faster with highly validated, pure and trusted compounds.
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Chemical Structure - (R,S)-Baclofen, GABAB agonist (AB120149)
  • Chemical Structure

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Chemical Structure - (R,S)-Baclofen, GABAB agonist (AB120149)

2D chemical structure image of ab120149, (R,S)-Baclofen, GABAB agonist

Key facts

CAS number

1134-47-0

Purity

>99%

Form

Solid

form

Molecular weight

213.66 Da

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>2</sub>ClNO<sub>2</sub>

PubChem

2284

Nature

Synthetic

Solubility

Soluble in 1 eq. NaOH to 100 mM

Biochemical name

Baclofen

Biological description

Selective GABAB receptor agonist. Antispasmodic.

Canonical smiles

C1=CC(=CC=C1C(CC(=O)O)CN)Cl

InChi

InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)

InChiKey

KPYSYYIEGFHWSV-UHFFFAOYSA-N

IUPAC Name

4-amino-3-(4-chlorophenyl)butanoic acid

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Biochemicals

AB120315

Picrotoxin, GABAA antagonist

Chemical Structure - Picrotoxin, GABAA antagonist (AB120315)

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Biochemicals

AB120337

CGP 55845 hydrochloride, GABAB antagonist

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Primary Antibodies

AB252881

Anti-GFP antibody [3H9]

BOND RX™ Validated|Recombinant|Lab Essentials|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [3H9] (AB252881)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

eLife 10: PubMed34369877

2021

Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex.

Applications

Unspecified application

Species

Unspecified reactive species

Chong Guo,Stephanie Rudolph,Morgan E Neuwirth,Wade G Regehr

Neuron 109:1791-1809.e11 PubMed33979635

2021

A photoswitchable GPCR-based opsin for presynaptic inhibition.

Applications

Unspecified application

Species

Unspecified reactive species

Bryan A Copits,Raaj Gowrishankar,Patrick R O'Neill,Jun-Nan Li,Kasey S Girven,Judy J Yoo,Xenia Meshik,Kyle E Parker,Skylar M Spangler,Abigail J Elerding,Bobbie J Brown,Sofia E Shirley,Kelly K L Ma,Alexis M Vasquez,M Christine Stander,Vani Kalyanaraman,Sherri K Vogt,Vijay K Samineni,Tommaso Patriarchi,Lin Tian,N Gautam,Roger K Sunahara,Robert W Gereau,Michael R Bruchas

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 36:472-87 PubMed20927050

2010

Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory.

Applications

Unspecified application

Species

Unspecified reactive species

Vasco C Sousa,Natália Assaife-Lopes,Joaquim A Ribeiro,Judith A Pratt,Ros R Brett,Ana M Sebastião
View all publications
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