(R,S)-Sulpiride, D2-like dopamine receptor antagonist

Key facts

CAS number

15676-16-1

Purity

>99%

Form

Solid

form

Molecular weight

341.4 Da

Molecular formula

C₁₅H₂₃N₃O₄S

PubChem

5355

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in 1 eq. HCl to 50 mM

Biochemical name

Sulpiride

Biological description

D2-like dopamine receptor antagonist. Shows antipsychotic activity. Active enantiomer (*S*)-sulpiride (ab120579) also available.

Canonical smiles

CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

InChi

InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)

InChiKey

BGRJTUBHPOOWDU-UHFFFAOYSA-N

IUPAC Name

N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide