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AB146049

RuBi-5-HT, caged-serotonin compound

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MW 736.64 g/mol. Highly water-soluble caged-serotonin (5-HT) compound based on ruthenium photochemistry. Excited with visible wavelengths and releases serotonin after one- or two-photon excitation. It has high quantum efficiency and can be used at low concentrations. Enables the photoactivation of 5-HT receptors with visible or two-photon light sources, achieving single cell, or even single spine, precision.
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Chemical Structure - RuBi-5-HT, caged-serotonin compound (AB146049)
  • Chemical Structure

Lab

Chemical Structure - RuBi-5-HT, caged-serotonin compound (AB146049)

2D chemical structure image of ab146049, RuBi-5-HT, caged-serotonin compound

Key facts

Form

Solid

form

Molecular weight

736.64 g/mol

Molecular formula

C<sub>3</sub><sub>3</sub>H<sub>3</sub><sub>7</sub>Cl<sub>2</sub>N<sub>6</sub>OPRu

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Highly water-soluble caged-serotonin (5-HT) compound based on ruthenium photochemistry. Excited with visible wavelengths and releases serotonin after one- or two-photon excitation. It has high quantum efficiency and can be used at low concentrations. Enables the photoactivation of 5-HT receptors with visible or two-photon light sources, achieving single cell, or even single spine, precision.

IUPAC Name

(Bis(2,2'-bipyridine-N,N')trimethylphosphine)-5-hydroxytryptamine ruthenium(2+) dichloride complex

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Product details

Sold under license from Columbia University; Patent Pending.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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Product promise

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