RuBi-Glutamate, caged-glutamate compound

Key facts

CAS number

1220121-59-4

Form

Solid

form

Molecular weight

970.5 Da

Molecular formula

C₂₈H₃₂F₁₂N₅Na₂O₄P₃Ru

PubChem

90488860

Nature

Synthetic

Solubility

Soluble in water to 20 mM

Biochemical name

RuBi-Glutamate

Biological description

Novel caged-glutamate compound based on ruthenium photochemistry. Excited with visible wavelengths and releases glutamate after one- or two-photon excitation. It has high quantum efficiency and can be used at low concentrations. Enables the photoactivation of neuronal dendrites and circuits with visible or two-photon light sources, achieving single cell, or even single spine, precision.

Also available in simple stock solutions (ab146718) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical smiles

CP(C)C.C1=CC=NC(=C1)C2=CC=CC=N2.C1=CC=NC(=C1)C2=CC=CC=N2.C(CC(=O)[O-])C(C(=O)[O-])N.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.[Na+].[Na+].[Ru+2]

InChi

InChI=1S/2C10H8N2.C5H9NO4.C3H9P.2F6P.2Na.Ru/c2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;6-3(5(9)10)1-2-4(7)8;1-4(2)3;2*1-7(2,3,4,5)6;;;/h2*1-8H;3H,1-2,6H2,(H,7,8)(H,9,10);1-3H3;;;;;/q;;;;2*-1;2*+1;+2/p-2

InChiKey

SQQVSHWHIPVYSZ-UHFFFAOYSA-L

IUPAC Name

disodium;2-aminopentanedioate;2-pyridin-2-ylpyridine;ruthenium(2+);trimethylphosphane;dihexafluorophosphate