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Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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MW 244.16 Da, Purity >98%. Broad spectrum agonist for AMPA and kainate receptors with no activity at NMDA or metabotropic receptors.
21826-03-02
> 98%
Solid
244.16 Da
C7H8N4O6
11096831
Synthetic
AMPA 1, AMPA 2, AMPA 4, AMPA-selective glutamate receptor 1, AMPA-selective glutamate receptor 2, AMPA-selective glutamate receptor 4, Excitatory amino acid receptor 2, GLUH1, GLUR4C, GRIA1_HUMAN, GRIA2_HUMAN, GRIA4_HUMAN, GRIK5_HUMAN, GluA 4, GluA1, GluA2, GluK5, GluR-1, GluR-2, GluR-4, GluR-A, GluR-B, GluR-D, GluR-K1, GluR-K2, GluRgamma2, Glutamate receptor, Glutamate receptor 1, Glutamate receptor 2, Glutamate receptor 4, Glutamate receptor KA-2, Glutamate receptor ionotrophic AMPA 4, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic AMPA 2, Glutamate receptor, ionotropic kainate 5 [Precursor], Glutamate receptor, ionotropic, kainate 5, Glutamate receptor, ionotropic, kainate 5 (gamma 2), HBGR1, HBGR2, Ionotropic Glutamate receptor 4, KA2, MGC118086, MGC133252, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, iGlu5, ionotropic kainate 5
MW 244.16 Da, Purity >98%. Broad spectrum agonist for AMPA and kainate receptors with no activity at NMDA or metabotropic receptors.
AMPA 1, AMPA 2, AMPA 4, AMPA-selective glutamate receptor 1, AMPA-selective glutamate receptor 2, AMPA-selective glutamate receptor 4, Excitatory amino acid receptor 2, GLUH1, GLUR4C, GRIA1_HUMAN, GRIA2_HUMAN, GRIA4_HUMAN, GRIK5_HUMAN, GluA 4, GluA1, GluA2, GluK5, GluR-1, GluR-2, GluR-4, GluR-A, GluR-B, GluR-D, GluR-K1, GluR-K2, GluRgamma2, Glutamate receptor, Glutamate receptor 1, Glutamate receptor 2, Glutamate receptor 4, Glutamate receptor KA-2, Glutamate receptor ionotrophic AMPA 4, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic AMPA 2, Glutamate receptor, ionotropic kainate 5 [Precursor], Glutamate receptor, ionotropic, kainate 5, Glutamate receptor, ionotropic, kainate 5 (gamma 2), HBGR1, HBGR2, Ionotropic Glutamate receptor 4, KA2, MGC118086, MGC133252, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, iGlu5, ionotropic kainate 5
21826-03-02
> 98%
Solid
244.16 Da
C7H8N4O6
11096831
Synthetic
3-(5-Nitro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine
Broad spectrum agonist for AMPA and kainate receptors with no activity at NMDA or metabotropic receptors
C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)[N+](=O)[O-]
C1=C(C(=O)NC(=O)N1C[C@@H](C(=O)O)N)[N+](=O)[O-]
InChI=1S/C7H8N4O6/c8-3(6(13)14)1-10-2-4(11(16)17)5(12)9-7(10)15/h2-3H,1,8H2,(H,13,14)(H,9,12,15)/t3-/m0/s1
IEBVITXSHAFLJR-VKHMYHEASA-N
(2S)-2-amino-3-(5-nitro-2,4-dioxopyrimidin-1-yl)propanoic acid
Ambient - Can Ship with Ice
+4°C
Store under desiccating conditions, The product can be stored for up to 12 months
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Full details and terms and conditions can be found here:
Terms & Conditions.
2D chemical structure image of ab120063, (S)-5-Nitrowillardiine, AMPA / kainate agonist
ab96379 staining MEK1 (phospho S298) in SK-N-SH cells treated with (S)-5-Nitrowillardiine (ab120063), by ICC/IF. Increase in MEK1 (phospho S298) expression correlates with increased concentration of (S)-5-Nitrowillardiine, as described in literature.
The cells were incubated at 37°C for 24h in media containing different concentrations of ab120063 ((S)-5-Nitrowillardiine) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab96379 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.
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