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AB120563

(S)-(-)-Raclopride, D2 receptor antagonist

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(1 Publication)

MW 347.24 g/mol, Purity >97%. High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.
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Chemical Structure - (S)-(-)-Raclopride, D2 receptor antagonist (AB120563)
  • Chemical Structure

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Chemical Structure - (S)-(-)-Raclopride, D2 receptor antagonist (AB120563)

2D chemical structure image of ab120563, (S)-(-)-Raclopride, D2receptor antagonist

Key facts

CAS number

84225-95-6

Purity

>97%

Form

Solid

form

Molecular weight

347.24 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 25 mM

Biological description

High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.

IUPAC Name

3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 42:112149 PubMed36821440

2023

Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience.

Applications

Unspecified application

Species

Unspecified reactive species

Yuma Nagai,Yuri Kisaka,Kento Nomura,Naoya Nishitani,Chihiro Andoh,Masashi Koda,Hiroyuki Kawai,Kaoru Seiriki,Kazuki Nagayasu,Atsushi Kasai,Hisashi Shirakawa,Takanobu Nakazawa,Hitoshi Hashimoto,Shuji Kaneko
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