MW 365.4 Da, Purity >97%. Selective STAT3 inhibitor (IC50 values are 86, 160, 166 and >300 μM for STAT3.STAT3, STAT1.STAT3 STAT1.STAT1 and STAT5.STAT5 DNA binding activity respectively). Suppresses fibronectin, α-SMA, and collagen I expression. Shows apoptotic antiproliferative effects. Shows anti-inflammatory and analgesic effects in vivo. Centrally active.
501919-59-1
> 97%
365.4 Da
C16H15NO7S
252682
Synthetic
MW 365.4 Da, Purity >97%. Selective STAT3 inhibitor (IC50 values are 86, 160, 166 and >300 μM for STAT3.STAT3, STAT1.STAT3 STAT1.STAT1 and STAT5.STAT5 DNA binding activity respectively). Suppresses fibronectin, α-SMA, and collagen I expression. Shows apoptotic antiproliferative effects. Shows anti-inflammatory and analgesic effects in vivo. Centrally active.
501919-59-1
> 97%
365.4 Da
C16H15NO7S
252682
Synthetic
2-Hydroxy-4-(2-(tosyloxy)acetamido)benzoic acid
Selective STAT3 inhibitor (IC50 values are 86, 160, 166 and >300 μM for STAT3.STAT3, STAT1.STAT3 STAT1.STAT1 and STAT5.STAT5 DNA binding activity respectively). Suppresses fibronectin, α-SMA, and collagen I expression. Shows apoptotic antiproliferative effects. Shows anti-inflammatory and analgesic effects in vivo. Centrally active.
CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O
InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
HWNUSGNZBAISFM-UHFFFAOYSA-N
2-hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid
Ambient - Can Ship with Ice
-20°C
-20°C
Store under desiccating conditions, The product can be stored for up to 12 months
This product is manufactured by BioVision, an Abcam company and was previously called 1775 Stat3 Inhibitor I, S3I-201. 1775-25 is the same size as the 25 mg size of ab141434.
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2D chemical structure image of ab141434, S3I-201, STAT3 inhibitor
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