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AB144353

SAG Analog (Highly Active), Shh and Smo agonist

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MW 524.5 Da, Purity >98%. Cell-permeable Shh and Smo agonist (Shh EC50 = 22 μM). Potent VEGF activator. Use in cell proliferation studies. Active in vitro.
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Chemical Structure - SAG Analog (Highly Active), Shh and Smo agonist (AB144353)
  • Chemical Structure

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Chemical Structure - SAG Analog (Highly Active), Shh and Smo agonist (AB144353)

2D chemical structure image of ab144353, SAG Analog (Highly Active), Shh and Smo agonist

Key facts

CAS number

1401532-77-1

Purity

>98%

Molecular weight

524.5 Da

Molecular formula

C<sub>2</sub><sub>8</sub>H<sub>2</sub><sub>7</sub>Cl<sub>2</sub>N<sub>3</sub>OS

PubChem

71451507

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

SAG Analog (LowTox)

Biological description

Cell-permeable Shh and Smo agonist (Shh EC50 = 22 μM). Potent VEGF activator. Use in cell proliferation studies. Active in vitro.

Canonical smiles

CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=C(S4)C=CC=C5Cl)Cl

InChi

InChI=1S/C28H27Cl2N3OS/c1-31-21-8-10-22(11-9-21)33(17-18-4-2-5-20(16-18)19-12-14-32-15-13-19)28(34)27-26(30)25-23(29)6-3-7-24(25)35-27/h2-7,12-16,21-22,31H,8-11,17H2,1H3

IUPAC Name

3,4-dichloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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