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MW 413.9 Da, Purity >98%. Water soluble, cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1 , RIP2 c-Raf and GSK3.
- CAS number
869185-85-3
- Purity
> 98%
- Form
Solid
- Molecular weight
413.9 Da
- Molecular formula
C21H17ClFN3OS
- PubChem identifier
16760644
- Nature
Synthetic
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MW 413.9 Da, Purity >98%. Water soluble, cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1 , RIP2 c-Raf and GSK3.
Key facts
- CAS number
869185-85-3
- Purity
> 98%
- Form
Solid
- Molecular weight
413.9 Da
- Molecular formula
C21H17ClFN3OS
- PubChem identifier
16760644
- Nature
Synthetic
- Biochemical name
SB 203580 Hydrochloride
- Biological description
Water soluble, cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1 , RIP2 c-Raf and GSK3.
- Canonical SMILES
CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl
- InChI
InChI=1S/C21H16FN3OS.ClH/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15;/h2-13H,1H3,(H,24,25);1H
- InChIKey
WOSGGXINSLMASH-UHFFFAOYSA-N
- IUPAC name
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine;hydrochloride
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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