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AB120895

SB 225002, non-peptide CXCR2 antagonist

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(1 Publication)

MW 352.14 g/mol, Purity >95%. A selective non-peptide CXCR2 antagonist. Inhibits IL-8 binding to CXCR2 (IC50 = 22 nM).
1 Images
Chemical Structure - SB 225002, non-peptide CXCR2 antagonist (AB120895)
  • Chemical Structure

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Chemical Structure - SB 225002, non-peptide CXCR2 antagonist (AB120895)

2D chemical structure image of ab120895, SB 225002, non-peptide CXCR2 antagonist

Key facts

CAS number

182498-32-4

Purity

>95%

Form

Solid

form

Molecular weight

352.14 g/mol

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>0</sub>BrN<sub>3</sub>O<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 75 mM

Soluble in ethanol to 25 mM

Biological description

A selective non-peptide CXCR2 antagonist. Inhibits IL-8 binding to CXCR2 (IC50 = 22 nM).

Canonical smiles

OC1=CC([N+]([O-])=O)=CC=C1NC(NC2=C(BR)C=CC=C2)=O

IUPAC Name

N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea

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Primary Antibodies

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer cell 40:818-834.e9 PubMed35868307

2022

Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Chen,Sujuan Yang,Jena Tavormina,Desiree Tampe,Michael Zeisberg,Huamin Wang,Krishnan K Mahadevan,Chang-Jiun Wu,Hikaru Sugimoto,Chia-Chi Chang,Robert R Jenq,Kathleen M McAndrews,Raghu Kalluri
View all publications
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