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MW 488.45 g/mol, Purity >99%.

Potent and selective 5-HT6 receptor antagonist (Ki = 1-2 nM). Displays >200-fold selectivity for 5-HT6 receptors (vs. other receptor binding sites and ion channels). Poor penetration of the blood-brain barrier. Nootropic effects in vivo.

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Images

Chemical Structure - SB 271046 hydrochloride, 5-HT6 antagonist (AB120589), expandable thumbnail

Key facts

CAS number
209481-24-3
Purity
> 99%
Form
Solid
Molecular weight
488.45 g/mol
Nature
Synthetic

Target data

Recommended products

MW 488.45 g/mol, Purity >99%.

Potent and selective 5-HT6 receptor antagonist (Ki = 1-2 nM). Displays >200-fold selectivity for 5-HT6 receptors (vs. other receptor binding sites and ion channels). Poor penetration of the blood-brain barrier. Nootropic effects in vivo.

Key facts

Purity
> 99%
Solubility

Soluble in DMSO to 100 mM.

Soluble in ethanol to 5 mM (with heating).

Biological description

Potent and selective 5-HT6 receptor antagonist (Ki = 1-2 nM). Displays >200-fold selectivity for 5-HT6 receptors (vs. other receptor binding sites and ion channels). Poor penetration of the blood-brain barrier. Nootropic effects in vivo.

IUPAC name
5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophen-2-sulfonamide hydrochloride

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - SB 271046 hydrochloride, 5-HT6 antagonist (ab120589), expandable thumbnail

    Chemical Structure - SB 271046 hydrochloride, 5-HT6 antagonist (ab120589)

    2D chemical structure image of ab120589, SB 271046 hydrochloride, 5-HT6 antagonist

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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