SB431542, ALK inhibitor (ab120163) is a potent and selective inhibitor of Activin receptor-like kinase (ALK). The molecular weight of SB431542 is 384.4 g/mol.
- Inhibits ALK 4, 5 (IC50 = 94 nM), and 7
- Available in different sizes to fit your experiment needs
View Alternative Names
AAT 5, ACTR-IB, ACTR-IC, ACV1B_HUMAN, ACV1C_HUMAN, ACVR 1B, ACVRLK 4, ACVRLK7, ALK-4, ALK-5, ALK-7, Activin A receptor type 1B, Activin A receptor type II like kinase, Activin A receptor type II like kinase 4, Activin A receptor type II like kinase 53kDa, Activin A receptor type II like kinase, 53kD, Activin A receptor, type IC, Activin A type 1B receptor, Activin A type IB receptor, Activin receptor type 1C precursor, Activin receptor type IB, Activin receptor type IC, Activin receptor type-1B, Activin receptor type-1C, Activin receptor-like kinase 4, Activin receptor-like kinase 5, Activin receptor-like kinase 7, Acvr1c, LDS1A, LDS2A, MSSE, SKR 2, SKR 4, Serine(threonine) protein kinase receptor R2, Serine/threonine-protein kinase receptor R2, Serine/threonine-protein kinase receptor R4, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFBR 1, TGFBR1 protein, TGFR1_HUMAN, TbetaR-I, Transforming growth factor beta receptor 1, Transforming growth factor beta receptor I, Transforming growth factor beta receptor I (activin A receptor type II like kinase, 53kD), Transforming growth factor-beta receptor type I, activin A receptor type II-like protein kinase of 53kD
- Chemical Structure
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Chemical Structure - SB431542, ALK inhibitor (AB120163)
2D chemical structure image of ab120163, SB431542, ALK inhibitor
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Publications (51)
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Theranostics 15:7127-7153 PubMed40585989
2025
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2409040 PubMed40245004
2025
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Communications biology 7:1561 PubMed39580573
2024
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Molecular medicine (Cambridge, Mass.) 30:227 PubMed39578767
2024
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Nature methods 22:68-81 PubMed39300283
2024
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American journal of physiology. Lung cellular and molecular physiology 326:L409-L418 PubMed38349124
2024
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International journal of chronic obstructive pulmonary disease 19:33-50 PubMed38197032
2024
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2304987 PubMed37991133
2023
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iScience 26:107265 PubMed37502260
2023
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Nature methods 20:1388-1399 PubMed37474806
2023
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