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AB269695

SB742457 (Intepirdine), 5-HT6 antagonist

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MW 353.4 Da. Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.
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Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (AB269695)
  • Chemical Structure

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Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (AB269695)

Chemical structure of SB742457 (Intepirdine), 5-HT6 antagonist, 607742-69-8

Key facts

CAS number

607742-69-8

Form

Solid

form

Molecular weight

353.4 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>1</sub><sub>9</sub>N<sub>3</sub>O<sub>2</sub>S

PubChem

11256720

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Soluble in ethanol to 5 mM

Biochemical name

Intepirdine

Biological description

Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.

Canonical smiles

C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4

InChi

InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2

InChiKey

JJZFWROHYSMCMU-UHFFFAOYSA-N

IUPAC Name

3-(benzenesulfonyl)-8-piperazin-1-ylquinoline

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Complementary Products

Biochemicals

AB120328

EMD 386088 hydrochloride, 5-HT6 agonist

Chemical Structure - EMD 386088 hydrochloride, 5-HT6 agonist (AB120328)

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Biochemicals

AB120332

SB 399885 hydrochloride, 5-HT6 antagonist

Chemical Structure - SB 399885 hydrochloride, 5-HT6 antagonist (AB120332)

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Cell Lines & Lysates

AB258561

Human PANK4 (Pantothenate kinase 4) knockout HEK-293T cell lysate

Sanger Sequencing - Human PANK4 (Pantothenate kinase 4) knockout HEK-293T cell lysate (AB258561)

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Assay Kits

AB215544

Mouse PDK4 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse PDK4 ELISA Kit (AB215544)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

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