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MW 353.4 Da. Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.

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Images

Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (AB269695), expandable thumbnail

Key facts

CAS number
607742-69-8
Form
Solid
Molecular weight
353.4 Da
Molecular formula
C19H19N3O2S
PubChem identifier
11256720
Nature
Synthetic

Target data

Recommended products

MW 353.4 Da. Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.

Key facts

PubChem identifier
11256720
Solubility

Soluble in DMSO to 50 mM.

Soluble in ethanol to 5 mM.

Biochemical name
Intepirdine
Biological description

Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.

Canonical SMILES
C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4
InChI
InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2
InChIKey
JJZFWROHYSMCMU-UHFFFAOYSA-N
IUPAC name
3-(benzenesulfonyl)-8-piperazin-1-ylquinoline

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C

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1 product image

  • Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (ab269695), expandable thumbnail

    Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (ab269695)

    Chemical structure of SB742457 (Intepirdine), 5-HT6 antagonist, 607742-69-8

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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