SBFI AM, fluorescent Na+ indicator

Key facts

CAS number

129423-53-6

Purity

>95%

Molecular weight

1127.1 Da

Molecular formula

C₅₆H₅₈N₂O₂₃

PubChem

4349546

Nature

Synthetic

Solubility

Soluble in DMSO to 1 mg/ml

Biochemical name

Sbfi-AM

Biological description

Cell-permeable, fluorescent Na+ indicator. Binds to Na+ ions (Kd = 7.4 mM). Fluorescence intensity increases upon Na+ binding.

Canonical smiles

CC(=O)OCOC(=O)C1=CC(=C(C=C1)C2=CC3=CC(=C(C=C3O2)N4CCOCCN(CCOCCOCC4)C5=C(C=C6C=C(OC6=C5)C7=C(C=C(C=C7)C(=O)OCOC(=O)C)C(=O)OCOC(=O)C)OC)OC)C(=O)OCOC(=O)C

InChi

InChI=1S/C56H58N2O23/c1-33(59)72-29-76-53(63)37-7-9-41(43(21-37)55(65)78-31-74-35(3)61)49-23-39-25-51(67-5)45(27-47(39)80-49)57-11-15-69-16-12-58(14-18-71-20-19-70-17-13-57)46-28-48-40(26-52(46)68-6)24-50(81-48)42-10-8-38(54(64)77-30-73-34(2)60)22-44(42)56(66)79-32-75-36(4)62/h7-10,21-28H,11-20,29-32H2,1-6H3

InChiKey

MWUYLQGOGOLRQS-UHFFFAOYSA-N

IUPAC Name

bis(acetyloxymethyl) 4-[6-[13-[2-[2,4-bis(acetyloxymethoxycarbonyl)phenyl]-5-methoxy-1-benzofuran-6-yl]-1,4,10-trioxa-7,13-diazacyclopentadec-7-yl]-5-methoxy-1-benzofuran-2-yl]benzene-1,3-dicarboxylate

Excitation/Emission

Ex: 334nm, Em: 505nm