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MW 352.7 Da, Purity >99%. Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.

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Images

Chemical Structure - SC-560, COX-1 inhibitor (AB120649), expandable thumbnail

Key facts

CAS number
188817-13-2
Purity
> 99%
Form
Solid
Molecular weight
352.7 Da
Molecular formula
C17H12ClF3N2O
PubChem identifier
4306515
Nature
Synthetic

Target data

Recommended products

MW 352.7 Da, Purity >99%. Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.

Key facts

Purity
> 99%
PubChem identifier
4306515
Solubility

Soluble in DMSO to 100 mM.

Soluble in ethanol to 25 mM.

Biochemical name
5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Biological description

Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 9 nM and 6.3 μM for COX-1 and COX-2, respectively). Displays anti-inflammatory, antitumor and antiviral activity. Orally active.

Canonical SMILES
COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl
InChI
InChI=1S/C17H12ClF3N2O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3
InChIKey
PQUGCKBLVKJMNT-UHFFFAOYSA-N
IUPAC name
5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - SC-560, COX-1 inhibitor (ab120649), expandable thumbnail

    Chemical Structure - SC-560, COX-1 inhibitor (ab120649)

    2D chemical structure image of ab120649, SC-560, COX-1 inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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